A meta-analysis of 12 studies of the risk of death after a brief resolved unexplained event (BRUE) found that such an event does not increase an infant’s risk of dying during his or her first year. The American Academy of Pediatrics (AAP) introduced BRUE, a sudden alteration in an infant’s breathing, color, tone, or responsiveness, as a replacement for “apparent life-threatening event” (ALTE) in a 2016 clinical practice guideline.
Infection with human rhinovirus (HRV) confirmed by polymerase chain reaction (PCR) does not decrease the likelihood of concurrent urinary tract infection (UTI) in infants aged from 1 to 90 days old, according to a study in well-appearing febrile infants in this age group.
Urinary neutrophil gelatinase-associated lipocalin (uNGAL) is highly sensitive and specific for diagnosing urinary tract infections (UTIs), according to a study in febrile children aged up to 24 months.
Compared with adolescents who use e-cigarettes with relatively low or no nicotine concentrations, those who use e-cigarettes with higher nicotine concentrations are more likely to progress to more frequent and intense combustible cigarette smoking and vaping.
A recent trial showed that a single intravenous infusion of a vector expressing a high specific-activity factor IX gene safely produces a sustained, effective level of factor IX coagulant activity in patients with hemophilia B.
Children who view movies with gun violence are more interested in guns and violence than their peers who do not have this exposure, a recent experiment showed.
Breastfeeding for a minimum of 2 months has a significant protective effect against sudden infant death syndrome (SIDS), almost halving the risk of its occurrence.
A comparison of a combination of oral morphine and oral ibuprofen with each of these drugs alone found that none of these options provided optimal analgesia for the pain of a musculoskeletal injury (MSK-I).
Using a cost-utility model of a hypothetical group of symptomatic children aged younger than 2 years who were diagnosed with acute otitis media (AOM), investigators evaluated whether antimicrobial therapy reduces time to symptom resolution, overall symptom burden, and persistence of infection.
A novel assay for distinguishing bacterial from viral infections significantly outperformed routine laboratory parameters and biomarkers in a study using serum remnants from children suspected to have acute infection.