1. When there is unclear information on pediatric dosing, an adult can be thought of as someone who weighs 40 kg (88 lb). Thus, a 100-lb, healthy 10-year-old child can usually be given an adult dose of medicine, and a 22-lb toddler could be given one-fourth of the adult dose.
2. Focalin XR releases faster than Concerta (Cmax1 1.5 h vs 3.7 h, respectively), according to the manufacturers.
3. You cannot open up Concerta and sprinkle it. The time release is in the delivery system (a piston that pushes the active ingredient through a tiny hole), and is not due to individually coated beads of medicine with different absorption rates, as with most other extended-release medicines.
4. As a rough guide, to convert Vyvance to Adderall XR, subtract 10 and divide by 2; eg, Vyvance 30 mg is equivalent to (30-10)/2=10 mg Adderall XR. As such, 2 Vyvance 30 mg are equivalent to Vyvance 50 mg, not 60 mg. This conversion, of course, does not work for the 10-mg Vyvance.