Although clinical trials are needed to understand and assess the role probiotics may play in children with autism, some data show that the microbiome in patients with autism is different from those without autism and that gastrointestinal symptoms of children with autism may mirror the symptoms of people with irritable bowel syndrome.
Currently, many families with an autistic child use alternative therapies to augment the standard of care. Among the conditions for which parents seek alternative therapies for their autistic child is for gastrointestinal symptoms. As such, there is speculation that probiotics may provide a therapeutic option for managing gastrointestinal symptoms but no evidence yet shows this.
Lenfestey MW, Neu J. Probiotics in Newborns and Children. Pediatr Clin N Am 2017;64:1271-1289.