In Drs. Gordon, Ordonez, and Jain’s article “Rifampin for biofilm-related infections,” the authors discussed the efficacy of specific therapies for biofilm-related infections. What about the role of biofilms in Staphylococcus aureus infections themselves? What enables them to challenge the immune system and facilitate antibiotic resistance?
Welcome to the matrix
Accept this month’s 5-item quiz challenge and see how well you know the wiles of this cunning pathogen that deploys a matrix “force field” to evade detection and eradication. What children are especially at risk? What treatment course gives the best outcomes?
1. A major difficulty in curing chronic persistent infections caused by Staphylococcus aureus (S aureus) is due to which of the following?
a) Lack of data on what causes chronic infection
b) Development of biofilms
c) Inadequate duration of antibiotic use
d) All of the above