Cardiology

The Orphan Drug Designation follows the receipt of Rare Pediatric Disease Designation from the FDA in January 2024.

A real-world analysis in the United States suggests hospital volume may not be the lone predictor of outcomes in pediatric cardiac surgery.

Decreasing severe adverse safety events (ASEs) could improve the poor outcomes associated with children with out-of-hospital cardiac arrest (OHCA), since 60% had at least 1 ASE.

In a study that measured blood pressure (BP) in multiple stages of life until young adulthood, investigators concluded that lower BP levels early in life, maintained through young adulthood, could reduce the risk of cardiovascular disease (CVD).

In the 18 studies that assessed the efficacy of closing a patent ductus arteriosus after 1 course of acetaminophen treatments, the results demonstrated that both oral and IV preparations were more effective than placebo.

Timing of administration of epinephrine was not associated with survival to discharge for pediatric out-of-hospital cardiac arrest patients, but overall use of epinephrine was.

The sudden cardiac arrest of Buffalo Bills safety Damar Hamlin on January 2 shocked the public, but the condition believed to have triggered his collapse is one that is more common in young athletes than any other group.

A recent study found that the risk of cardiovascular diseases was not significantly greater in patients taking medications for attention-deficit/hyperactivity disorder (ADHD), but investigators were not able to rule out a mild risk increase.

Data from the DANish LIFE course cohort indicated that individuals with high adversity in childhood were at a greater risk of developing cardiovascular diseases than those with low adversity.

Less severe cases of homozygous familial hypercholesterolemia often go undiagnosed and untreated, according to data presented at the AAP National Conference & Exhibition in Anaheim, California from October 7-11.

Based on an investigation of associations between patterns of growth in infant weight and adult-onset coronary heart disease, the answer seems to be no.

Screening and early-life interventions for these patients may prevent cardiometabolic outcomes, according to investigators.

Evinacumab phase 3 results show a 48% LDL-C reduction in children with homozygous familial hypercholesterolemia.

Obstructive sleep apnea has previously been associated with pulmonary hypertension in literature, with investigators citing a “complex and bidirectional relationship” between the 2 conditions.

A visit to the emergency department for supraventricular tachycardia (SVT) will often result in a battery of tests. The often normal results for those tests raise the question of whether they're needed.

Children with sickle cell anemia (SCA) should receive a yearly screening to identify stroke risk, but a new investigation indicates that many affected children may not be getting it.

Sometimes Kawasaki disease doesn’t respond to treatment. An investigation looks into whether a second course of standard treatment performed better than treating with infliximab.

A female aged 13 years with morbid obesity and recent hospitalization for pyelonephritis presents with abdominal pain, tachycardia, and shortness of breath. What's the diagnosis?

A research letter offers some of the first data on the long-term outcomes of the first children diagnosed with multisystem inflammatory syndrome in children (MIS-C).

A study examines whether a positive test for bronchiolitis increases morbidity or mortality in patients undergoing cardiac surgery.

Sleep apnea is linked to hypertension in adults. A report investigates whether this link exists in childhood obstructive sleep apnea.

An investigation offers insights on clinical manifestations of multisystem inflammatory syndrome in children (MIS-C) as well as information on geographic distribution.

Given the high prevalence of Kawasaki disease during the pandemic, Japanese investigators determined that droplet or contact transmission of pathogens is likely not a major route causing the development of the disease.

A higher risk of adult-onset heart failure was found in this Swedish study that investigated its association with singleton live births before 37 weeks gestation.

The US Food and Drug Administration (FDA) has given the stamp of approval for Harmony Transcatheter Pulmonary Valve System, a first in the world device to treat congenital heart defects.

A case series offers insight on how to separate multisystem inflammatory syndrome in children (MIS-C) and severe acute coronavirus 2019 disease (COVID-19).

A report adds cardiovascular health in pregnancy as another determining factor of a child’s future health.

An investigation provides much needed data on mental health issues in patients with congenital heart disease.

Many things in childhood can have a lifelong impact. A new study sheds light on how peer marginalization can impact cardiovascular outcomes in adulthood.

Dialysis can help extend the life expectancy of patients with kidney disease, but it also has an impact on mortality. A new study looks at how cardiovascular mortality trends have changed for patients on dialysis.