HCP Live
Contagion LiveCGT LiveNeurology LiveHCP LiveOncology LiveContemporary PediatricsContemporary OBGYN

Postpartum depression linked to atopic dermatitis in children

Contemporary PEDS Journal, Vol 37 No 4, Volume 37, Issue 4

Postpartum depression has a number of profound effects. A new study indicates that postpartum depression could increase the risk of atopic dermatitis, especially at ages 5 and 9 years.

Postpartum depression can have a number of profound effects not only on the mother, but for children as well. A new study published in Dermatitis indicates that children with mothers who had postpartum depression may have an increased risk of developing atopic dermatitis (AD).1

The investigators used the Fragile Families and Child Wellbeing Study (FFCWS), which is a prospective cohort study of 4898 children who were born in 20 metropolitan cities in the United States. They found that a history of postpartum depression was linked with childhood AD (multivariable logistic regression; adjusted odds ratio [aOR], 1.32; 95% confidence interval [CI], 1.06-1.64). The association was particularly pronounced in children aged 5 years (aOR, 1.34; 95% CI, 1.04-1.73) and 9 years (aOR, 1.37; 95% CI, 1.10-1.70).

A history of maternal depression increases AD risk

Additionally, postpartum depression was linked to more persistent AD (present at age 2 years: aOR, 1.58; 95% CI, 1.12-2.22; at 3 years: aOR, 1.73; 95% CI, 1.15-2.60). A history of maternal depression in the past year was linked to significantly higher odds of AD in children aged 5 years (aOR, 1.54; 95% CI, 1.20-1.99); 9 years (aOR, 1.36; 95% CI, 1.10-1.71); and 15 years (aOR, 1.43; 95% CI, 1.13-1.80).

Furthermore, mother’s depression was associated with higher odds of AD in offspring during 1 year (aOR, 1.50; 95% CI, 1.16-1.94), 2 years (aOR, 1.60; 95% CI, 1.16-2.19), or all 3 years of interviews (aOR, 1.61; 95% CI, 1.06-2.45).

The researchers concluded that depression in the postpartum period and beyond appears to be linked with AD in both childhood and adolescence.



1. McKenzie C, Silverberg J. Maternal depression and atopic dermatitis in American children and adolescents. Dermatitis. 2020;31(1):75-80.