Respiratory

Cyclo Therapeutics has enrolled 10 patients in a single-arm sub-study treating newborns to 3 years of age, evaluating the Trappsol Cyclo in the youngest subsets.

Allergic sensitization was more prominent in severe phenotypes but did not explain seasonal differences.

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Can you diagnose this patient?

Editor-in-chief Tina Tan, MD, FAAP, FIDSA, FPIDS, highlights the January/February, 2025, issue of Contemporary Pediatrics.

The patient had increased her vape use recently, but did not disclose when she started, or how much she vaped.

Detectable TTE in children's urine were 'significantly higher' in homes with reported in-home cannabis smoking.

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The study within a single health care system revealed that most infants born prior to December received the nirsevimab monoclonal antibody.

The federal agency has set a target action date of June 10, 2025 for potential approval.

The halt follows a severe respiratory disease safety signal observed in a July 2024 phase 1 trial of Moderna's mRNA-1345 and mRNA-1365 vaccine candidates.

Zelicapavir demonstrated a favorable safety profile and was well-tolerated. The N-protein inhibitor has been granted Fast Track Designation by the FDA.

Results demonstrated that those with earlier asthma onset had slower development of episodic memory.

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A further understanding of the role SARS-CoV-2 plays in T2D incidence can add an important component to benefit and risk considerations to prevent COVID-19.

The primary endpoint of the study was survival free of BPD at 36 weeks' postmenstrual age.

"The novel RSV prevention strategies may reduce ICU morbidity and mortality for children," the study authors concluded.

There were no treatment or RSV-related deaths during the study.

Infants were 22% less likely to develop asthma in early childhood if there were only fed breast milk during birth hospitalization, per a study presented at the 2024 AAP National Conference & Exhibition.

The landmark indication is supported by a couple of pivotal trials assessing dupilumab for patients with chronic rhinosinusitis with nasal polyps, as well as a pediatric severe asthma trial assessing the biologic.

"This is another example of how people trying to find a useful therapeutic role for magnesium usually come up short," stated Jon Matthew Farber, MD.

Editor-in-chief Tina Tan, MD, FAAP, FIDSA, FPIDS, highlights the August 2024 issue of Contemporary Pediatrics.

Healthcare providers should maintain heightened suspicion of parvovirus B19 in individuals presenting with symptoms, particularly those at high risk.

An interactive text message program boosted vaping cessation rates by 35% among adolescents compared to a control group, a JAMA study found.

An 11-year-old boy with a history of asthma and allergic rhinitis presented to the emergency department (ED) with worsening fatigue, minimal responsivity to external stimuli, and diffuse muscle weakness for 2 months.

A pair of medical directors involved in the transplant clinical space provide commentary on heart and lung transplants in the pediatric population.

Editor-in-chief Tina Tan, MD, FAAP, FIDSA, FPIDS, highlights the August 2024 issue of Contemporary Pediatrics.

These data highlighted new findings on the experiences of children aged 6 to 11 with uncontrolled type 2 asthma treated with dupilumab.

These data highlighted the association of moderate air pollution exposure during pregnancy, infancy, and early childhood on pulmonary function at school age.

Merck announced clesrovimab met all primary safety and efficacy endpoints, with additional detailed findings to be presented at an upcoming scientific congress.