Respiratory

M pneumoniae infection is not a reportable disease, and testing is often not performed in the outpatient setting, limiting estimates of clinical prevalence and delaying recognition of community epidemics.

Cyclo Therapeutics has enrolled 10 patients in a single-arm sub-study treating newborns to 3 years of age, evaluating the Trappsol Cyclo in the youngest subsets.

Allergic sensitization was more prominent in severe phenotypes but did not explain seasonal differences.

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Can you diagnose this patient?

Editor-in-chief Tina Tan, MD, FAAP, FIDSA, FPIDS, highlights the January/February, 2025, issue of Contemporary Pediatrics.

The patient had increased her vape use recently, but did not disclose when she started, or how much she vaped.

Detectable TTE in children's urine were 'significantly higher' in homes with reported in-home cannabis smoking.

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The study within a single health care system revealed that most infants born prior to December received the nirsevimab monoclonal antibody.

The federal agency has set a target action date of June 10, 2025 for potential approval.

The halt follows a severe respiratory disease safety signal observed in a July 2024 phase 1 trial of Moderna's mRNA-1345 and mRNA-1365 vaccine candidates.

Zelicapavir demonstrated a favorable safety profile and was well-tolerated. The N-protein inhibitor has been granted Fast Track Designation by the FDA.

Results demonstrated that those with earlier asthma onset had slower development of episodic memory.

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A further understanding of the role SARS-CoV-2 plays in T2D incidence can add an important component to benefit and risk considerations to prevent COVID-19.

The primary endpoint of the study was survival free of BPD at 36 weeks' postmenstrual age.

"The novel RSV prevention strategies may reduce ICU morbidity and mortality for children," the study authors concluded.

Octavio Ramilo, MD, joins us to discuss new clesrovimab phase 2b/3 study data presented at IDWeek 2024 in Los Angeles, California.

There were no treatment or RSV-related deaths during the study.

Contemporary Pediatrics' editor-in-chief Tina Tan, MD, FAAP, FIDSA, FPIDS, talks RSV immunization and the availability of prevention tools.

Infants were 22% less likely to develop asthma in early childhood if there were only fed breast milk during birth hospitalization, per a study presented at the 2024 AAP National Conference & Exhibition.

The landmark indication is supported by a couple of pivotal trials assessing dupilumab for patients with chronic rhinosinusitis with nasal polyps, as well as a pediatric severe asthma trial assessing the biologic.

"This is another example of how people trying to find a useful therapeutic role for magnesium usually come up short," stated Jon Matthew Farber, MD.

Editor-in-chief Tina Tan, MD, FAAP, FIDSA, FPIDS, highlights the August 2024 issue of Contemporary Pediatrics.