Marian Freedman

Investigators asked the children’s parents about the history of musculoskeletal-related disease, observed the children’s gait, and performed physical examinations.

A systematic review and meta-analysis found that such sequencing indeed has an equivalent high genetic diagnostic yield in cerebral palsy, which supports including this neurodevelopmental disorder among those for which diagnostic exome sequencing should be used.

To assess the role of familial factors, investigators analyzed data for a family-based group created from another Swedish national register that included 833,172 individuals without ADHD with different levels of relatedness to the individuals with ADHD and a group of matched controls.

The 20 children in the investigation had been diagnosed with ASD by PCPs who were trained using the ECHO (Extension for Community Healthcare Outcomes) Autism Screening Tool for Autism in Toddlers and Young Children (STAT).

The authors noted that right-sided EA is often misdiagnosed as acute appendicitis, and that steady but sharp and nonmigratory pain in either of the lower abdominal quadrants should raise suspicion of EA.

The authors noted that there is evidence that recommending early introduction of peanut without prior testing is safe and effective in increasing early peanut introduction to infants, even those at high risk.

In the 18 studies that assessed the efficacy of closing a patent ductus arteriosus after 1 course of acetaminophen treatments, the results demonstrated that both oral and IV preparations were more effective than placebo.

After 12 weeks of treatment, 55.8% of participants receiving IDP-126 experienced at least a 70% reduction from baseline in inflammatory and noninflammatory lesions

"I am impressed with how far we have come in being able to suture much more humanely and in how well so many of these youngsters did without sedation," said Jon Matthew Farber, MD.

Providers who refer patients for clinical hypnosis must ensure that the chosen hypnotherapist has appropriate knowledge about the patient’s gastrointestinal condition and has conducted clinical hypnosis for it.

Assessing pain in nonverbal patients remains very difficult, including being able to distinguish it from “behavior” (eg, self-stimulation), says Jon Matthew Farber, MD.

Patients first reported systemic symptoms, such as fevers, headache, and myalgias; vulvar symptoms, which included vulvar pain and dysuria, typically developed 2 days after vaccination and peaked within 5 days.

In choosing a treatment plan, many health care providers reported that they initiate treatment of systemic juvenile idiopathic arthritis (sJIA) with a biologic agent most of the time.

A 12-week study in Egypt of the efficacy of fluoxetine (a selective serotonin reuptake inhibitor) in children with treatment-refractory nocturnal enuresis (NE) found that though the treatment achieved a good initial response, it was not sustainable.

In children who are subject to migraine attacks, vitamin D supplementation may be an effective and safe adjunctive prophylactic therapy to topiramate, results of a study in Saudi Arabia showed.

Although avascular necrosis (AVN) is believed to be an iatrogenic complication following treatment of developmental dysplasia of the hip, an investigation in China found 2 characteristics associated with the condition: the likelihood of AVN increases with both the grade of dislocation and of underdevelopment of the ossific nucleus.

Lisdexamfetamine dimesaylate was associated with reduced ADHD symptoms in children aged 4 to 5 years.

A digital sleep strategy may reduce sleep problems for children.

A study found similar bone mineral density between children with and without type 1 diabetes.

Many children continue to use melatonin for years after being prescribed the medication, according to a recent study.

With instances of SBI lowering in children with sickle cell disease, authors of a recent study recommended continued management through empirical antibiotics.

In a recent study, rate of ankle arthritis did not differ significantly between children with JIA and children without JIA.

A retrospective study found that postmenarchal women with a renal anomaly were also at risk of having a Müllerian anomaly.

Treatment of the various types of spinal muscular atrophy with approved therapies resulted in an array of improvements, according to a review of 22 studies.

Based on an investigation of associations between patterns of growth in infant weight and adult-onset coronary heart disease, the answer seems to be no.

For the first time, investigators broke down into narrow age bands morbidity and mortality estimates for respiratory syncytial virus (RSV).

Most children outgrow an adverse drug reaction to oral antibiotics, according to an Icelandic study.

A survey saw that of teenagers who sought care in the ED and were prescribed outpatient treatment, fewer than half who received an STI diagnosis filled their prescriptions.

Results of a study in patients with Hirschsprung disease for whom surgery was anticipated but had not yet been performed found that 17% developed complications.

For years, teenagers have been told to avoid certain foods to reduce acne. A review article examines the evidence.