Morgan Ebert, Managing Editor

Long-term data show sustained survival, immune recovery, and metabolic correction after lentiviral gene therapy for ADA-SCID, with no vector-related safety events.

National CPS data from 2012-2023 show declines in confirmed child maltreatment, but disparities remained, particularly among Black and female children.

FDA adds boxed warning to Elevidys and limits use to ambulatory DMD patients ≥4 years after reports of fatal acute liver failure in non-ambulatory patients.

Sub-analysis of ADORING trials shows VTAMA cream improved skin clearance, symptoms, and patient-reported outcomes in children aged 2-17.

Study of 99 pediatric patients found clinically significant CNVs in 30% of cases, supporting CMA as a first-tier test for developmental delay and ID.

FDA grants Breakthrough Device Designation to GeneDx genome and exome tests supporting diagnosis of life-threatening genetic disorders.

A health system–wide lipid screening pathway significantly increased pediatric screening rates across a large primary care network.

FDA approves first irritable bowel syndrome with constipation (IBS-C) treatment, linaclotide (Linzess), for children aged 7 years and older based on pediatric and adult trial data.

New 2025 AHA CPR guidelines update choking response, opioid overdose care, and pediatric training to improve survival outcomes.

FDA approves Kygevvi, the first therapy for thymidine kinase 2 deficiency, a rare mitochondrial disease marked by muscle weakness and early death.

A look back at the FDA submissions and regulatory decisions in the pediatric health care space from October 2025.

Take a quick look at everything you may have missed this month, including the top FDA approvals and latest clinical updates.

A review highlights the benefits and risks of artificial sweeteners in glycemic control, insulin sensitivity, and gut microbiota balance.

FDA moves to remove unapproved ingestible fluoride drugs for children, citing microbiome and thyroid concerns.

In this Q&A, Abby Nerlinger, MD, breaks down how pediatricians can provide detailed care for children with military connections, based on a session presented at the 2025 AAP National Conference & Exhibition.

Unintentional marijuana ingestions in children under 5 rose over 1,000% in 7 years, with edibles and pandemic-related factors fueling the trend.

A study of 3,438 toddlers found slightly lower emotional and behavioral problems among children assessed during the COVID-19 pandemic.

IDWeek 2025 heads to Atlanta October 19–22 with cutting-edge sessions on AMR, AI, vaccines, HIV, pediatrics, and global health challenges.

FDA accepts MannKind’s sBLA for Afrezza in children and adolescents with diabetes.

Training tools and EHR prompts boosted pediatricians’ adherence to early peanut introduction guidelines in a new trial.

Ellen Fremion, MD, outlines strategies to support smooth transitions from pediatric to adult care, stressing early planning and strong collaboration.

View our Q3 2025 recap of standout pediatric news from FDA regulatory updates, clinical trial results, and expert commentary.

Remote monitoring in pediatrics shows promise for improving outcomes, but device design, workflow integration, and reimbursement remain key.

Take a quick look at everything you may have missed this month, including the top FDA approvals and latest clinical updates.

A look back at the FDA submissions and regulatory decisions in the pediatric health care space from September 2025.

Decline in maternal smoking linked to fewer US newborns with gastroschisis, highlighting benefits of public health efforts.

Over half of youth firearm suicides involved a parent’s gun, with most stored unlocked and loaded, underscoring the need for secure storage.

Mothers with multiple adverse childhood experiences faced double the risk of preterm birth, highlighting intergenerational health effects.

Youth suicides by sodium nitrite/nitrate are rising, highlighting prevention gaps and opportunities for early medical and public health intervention.

Federal backup camera mandate cut pediatric backover injuries and deaths, though risks remain for children in older vehicles without cameras.