Morgan Ebert, Executive Editor

AAP issues new report urging early, routine screening for mental, emotional, and behavioral problems in pediatric care to improve outcomes.

Results from a cross-sectional study find large proportions of obesity-related conditions in US youth are attributable to obesity and, to a lesser extent, overweight.

FDA approves updated COVID-19 vaccines for 2025-2026 but limits pediatric access, restricting use to older and high-risk groups.

A recent study found child depression predicted later maternal depression, highlighting the need for family-centered care.

A Rutgers-led study found genetics, personality traits, and environment uniquely shape early adolescent alcohol use, guiding prevention efforts.

Less than half of US adolescents with major depressive episode received treatment in 2022, with disparities by race, gender, and geography.

Large Korean study finds no link between prenatal or infant antibiotic exposure and autoimmune disease risk in children.

Higher omega-3 intake may protect children from myopia, while diets high in saturated fats may raise risk, study finds.

Immune surveillance study shows pandemic interventions suppressed viral exposure in children, driving post-COVID resurgence and future outbreak risk.

In recent studies, donidalorsen (Dawnzera) has demonstrated durable efficacy and long-term disease control.

Low-dose methylprednisolone is as effective as high-dose for severe pediatric MPP and has fewer side effects, supporting safer treatment strategies.

Controlling childhood EoE inflammation improves esophageal flexibility, reduces dysphagia risk, and may predict need for stricture dilation.

High-dose centanafadine significantly improved ADHD symptoms in children aged 6 to 12 years and was well tolerated, according to findings from a phase 3 clinical trial.

Biennial HPV testing and higher vaccination rates could help South Korea eliminate cervical cancer up to a decade earlier than current policy.

AAP updates guidance on recognizing and managing iatrogenic opioid dependence and withdrawal in children prescribed opioids.

Survey finds 30% of children missing school due to anxiety miss over a week; experts urge early intervention and therapy to address school avoidance.

Higher maternal vitamin D in early pregnancy linked to better fluid and overall cognition in children, especially among those of Black mothers.

FDA approves first generic iron sucrose injection for treating iron deficiency anemia in CKD patients 2 years and older.

FDA accepts priority review of gepotidacin, a first-in-class oral antibiotic, for treating uncomplicated urogenital gonorrhea in patients ≥12 years.

Pharmacotherapy use for pediatric obesity rose after AAP’s 2023 guidelines, though overall rates remain low compared to nutrition counseling.

A US study finds influenza-associated necrotizing encephalopathy in children has high mortality and disability, underscoring need for early care.

A look back at the FDA submissions and regulatory decisions in the pediatric health care space from July 2025.

Take a quick look at everything you may have missed last month, including the top FDA approvals and latest clinical updates.

The FDA approved concizumab-mtci (Alhemo; Novo Nordisk) for hemophilia A/B without inhibitors, offering once-daily subcutaneous prophylaxis that significantly reduces bleeding rates.

Pediatricians are urged to follow 2024 guidelines amid ACIP upheaval, vaccine hesitancy, and access issues as children head back to school.

Many families face common potty training challenges, including anxiety and setbacks, highlighting the need for patience and personalized strategies.

The FDA has approved avatrombopag and new sprinkle formulation for children ≥1 year with chronic ITP, offering an oral, food-flexible treatment option.

Most youth with type 1 diabetes in sub-Saharan Africa lack autoimmune markers, suggesting a distinct, non-autoimmune form of insulin-deficient diabetes.

Nirsevimab reduced RSV-related illness by up to 98% and lowered the amount of hospitalizations and health care use among healthy term infants in a real-world study.

A new polygenic risk score enhances obesity risk prediction from childhood to adulthood, offering new insights for early intervention and prevention strategies.