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Thank you for visiting the Contemporary Pediatrics® website. Take a look at some of our top stories from last week (Monday, January 27, to Friday, January 31, 2025), and click on each link to read and watch anything you may have missed.
Key atopic dermatitis approvals are changing the treatment landscape
2024 brought significant advancements in atopic dermatitis (AD) treatment, with the FDA approving new therapies that expand the options available to pediatric providers. These approvals include innovative nonsteroidal topicals and advanced systemic treatments, offering new hope for better disease management.
In this article, experts Lawrence Eichenfield, MD, and Russell Libby, MD, FAAP, discuss how these new therapies fit into the evolving AD treatment landscape. They highlight the impact on pediatric patients, the growing role of nonsteroidal options, and what primary care providers should know to optimize patient care.
“We’re in a new era of AD treatment, with options that go beyond just managing symptoms to truly improving long-term disease control,” says Eichenfield. “For pediatricians, understanding these new therapies means being able to offer families more choices and better outcomes, whether it’s through advanced topicals or systemic treatments for more severe cases.”
Click here for treatment data, manufacturers, and additional commentary in an easy-to-watch video form.
Puzzler: 14-year-old with asthma, vomiting, and vape use presents with chest pain
A 14-year-old girl presented to her primary care office with 2 weeks of vomiting that began when she tried to eat breakfast. She said she was feeling well up until that point, but then developed sudden onset vomiting and constant, 7/10, non-radiating chest pain centrally located at about the level of the second rib that remained unchanged since onset and slightly worsened when trying to eat. She was able to take in liquids but vomited all food, despite having an appetite. She denied feeling the food get stuck in her throat and endorsed continued vomiting of meals within 2 minutes of eating. She denied blood in the vomit and denied any abdominal pain.
Urination was unchanged, and stools, although infrequent because of a lack of eating, continued to have their normal consistency and color. The patient did endorse some mild shortness of breath. This started around the same time as the other symptoms, but did not find it very bothersome. Her last sexual encounter was 3 months prior to this visit, just prior to Nexplanon insertion. Her last menstrual period was 2 months prior to the visit.
On review of systems, she did not endorse palpitations, syncope, lightheadedness. She had increased her vape use recently but did not disclose when she started or how much she vaped. She had no recent travel and had not identified any extremity swelling. She was unsure if she had lost weight but had not been trying to lose any.
Click here for the full case presentation, differential diagnosis, and the correct patient diagnosis.
Sudden unexpected infant death is increasing, new study finds
A study published in JAMA Pediatrics analyzed trends in sudden unexplained infant death (SUID) in the U.S. from 1999 to 2022 using CDC WONDER data. Researchers found that while overall infant mortality declined by 24.2%, SUID rates increased from 89.9 to 100.5 per 100,000 between 2020 and 2022. This rise was more generalized than previously thought, affecting infants across multiple racial and ethnic groups. However, disparities persist, with SUID rates significantly higher among Black and American Indian/Alaska Native infants compared to Asian and White infants.
Potential contributors to this increase include COVID-19, maternal opioid use, and unsafe sleep practices influenced by social media. Study lead author Elizabeth Wolf, MD, emphasizes the need for strengthened public health messaging and safe sleep education at well-child visits. She also advocates for stricter regulations on unsafe infant sleep products, stressing that while not all SUID cases are preventable, some risks can be mitigated.
Click here for full study results.
Tina Tan, MD, comments on a severe respiratory season, stresses timely vaccination