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Celiac disease: Fundamentals for pediatricians

Prompt diagnosis and treatment of what was once considered a rare disorder of early childhood can eliminate symptoms and prevent long-term problems, such as osteoporosis and intestinal cancer.

This review discusses the epidemiology, clinical manifestations, diagnosis, and treatment of CD, emphasizing clinical recognition of children who may have CD and use of appropriate serologic tests to identify those who should be referred for definitive diagnosis and treatment. We encourage the reader to review the "Guideline for the diagnosis and treatment of celiac disease in children" developed by the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition.1 This clinical practice guideline can be viewed at http://www.naspghan.org/ or http://www.celiachealth.org/.

How common is CD?

What are the clinical manifestations?