Gene defects affects likelihood of nicotine dependence


Those were the findings of a prospective study conducted in 281 7th grade students from 10 schools in Canada who had begun to smoke but were not yet addicted. Participants were followed for, on average, 29.9 months; they completed questionnaires about their smoking every three or four months during the school year, and provided blood samples. During follow-up from time of first inhalation, 29% of the youngsters became dependent on nicotine. Subjects with the genetic variant that caused slowed inactivation of nicotine were almost three times more likely to develop tobacco dependence (O'Loughlin J et al: Tobacco Control 2004;13:422).

Commentary: Another example of how genetic screening may change pediatric practice! One day, we may target counseling based on how likely a patient is to develop a disease or, as in this case, an addiction.

Related Videos
Screening for and treating the metatarsus adductus foot deformity |  Image Credit: UNFO md ltd
Wendy Ripple, MD
Wendy Ripple, MD
Courtney Nelson, MD
DB-OTO improved hearing to normal in child with profound genetic deafness | Image Credit: © Marija - © Marija -
Carissa Baker-Smith
Perry Roy, MD
Perry Roy, MD | Image Credit: Carolina Attention Specialists
Angela Nash, PhD, APRN, CPNP-PC, PMHS | Image credit: UTHealth Houston
© 2024 MJH Life Sciences

All rights reserved.