Infections during the first year of life may increase the risk of rheumatoid arthritis and juvenile idiopathic arthritis later in life, according to new findings.
Infections during the first year of life may increase the risk of rheumatoid arthritis and juvenile idiopathic arthritis (JIA) later in life, according to new findings.
As reported at the 2008 Annual Congress of the European League Against Rheumatism in Paris, France, researchers reviewed data of persons born between 1973 and 2002 in Sweden, and included 333 rheumatoid arthritis patients and 3,334 JIA patients for their study.
The analysis showed that an increase in infections within the first 12 months of life was associated with an increased risk of developing JIA (odds ratio = 0.7) and sero-negative rheumatoid arthritis (odds ratio = 1.5).
Other potential risk factors for these arthritic disorders included low birth weight and duration of the gestational period. In particular, a gestational period longer than 42 weeks was a potential risk factor for developing JIA, the investigators found.
CDC recommends nirsevimab be prioritized for highest-risk infants amid limited availability
October 26th 2023The Centers for Disease Control and Prevention is advising providers to prioritize 100 mg doses of nirsevimab, a monoclonal antibody FDA-approved to prevent respiratory syncytial virus (RSV), for infants at the highest risk of severe RSV disease.
Navigating a complex case of pediatric COVID-19 with immunomodulatory therapies
October 21st 2023Eculizumab and anakinra should be considered in critically ill patients with severe infections that require immunomodulating therapies for life-threatening dysregulation, according to a poster session at the 2023 American Academy of Pediatrics National Conference & Exhibition.