Obesity in Pregnancy Increases Risk of Neural Tube Defects

Article

Being overweight or obese increases the risk of having a pregnancy affected by neural tube defects, with the risk for severely obese women triple that of normal weight women, according to a review published in the June issue of the American Journal of Obstetrics & Gynecology.

MONDAY, June 9 (HealthDay News) -- Being overweight or obese increases the risk of having a pregnancy affected by neural tube defects, with the risk for severely obese women triple that of normal weight women, according to a review published in the June issue of the American Journal of Obstetrics & Gynecology.

Sonja A. Rasmussen, M.D., of the U.S. Centers for Disease Control and Prevention in Atlanta, and colleagues conducted a meta-analysis of 12 studies on the relationship between maternal obesity and the risk of neural tube defects.

Compared to normal weight women, overweight, obese and severely obese women were 1.22, 1.70 and 3.11 times more likely, respectively, to have a pregnancy affected by neural tube defects, the researchers found.

"The reasons for this association are unknown. This quantitative estimate of the risk adds to our understanding of the total public health effects of obesity among women of reproductive age and provides additional information for appropriate interpretation of trends in neural tube defects prevalence," the authors write. "Future assessments of trends in neural tube defects prevalence might benefit from taking into account the effects of the changing prevalence of maternal obesity."

AbstractFull Text (subscription or payment may be required)

Copyright © 2008 ScoutNews, LLC. All rights reserved.

Recent Videos
cUTI Roundtable: Discussing and diagnosing these difficult infections
Willough Jenkins, MD
Discussing health care sustainability, climate change, and WHO's One Health goal | Image credit: Provided by Shreya Doshi
Willough Jenkins, MD
Screening for and treating the metatarsus adductus foot deformity |  Image Credit: UNFO md ltd
Wendy Ripple, MD
Wendy Ripple, MD
Courtney Nelson, MD
DB-OTO improved hearing to normal in child with profound genetic deafness | Image Credit: © Marija - © Marija - stock.adobe.com.
© 2024 MJH Life Sciences

All rights reserved.