Joshua Fitch, Senior Editor

Though revisions have been made to the emergency use authorization (EUA), the FDA stated in a press release that the EUA will continue to authorize emergency use in children aged 12 years and older who are at high risk of severe COVID-19.

Review some of the top stories from the Contemporary Pediatrics website over the last week, and catch up on anything you may have missed.

In this Contemporary Pediatrics Q+A interview, Weily Soong, MD, breaks down FDA-approved tralokinumab-ldrm for patients aged 12 to 17 years with moderate-to-severe atopic dermatitis.

Take this Contemporary Pediatrics quiz, and see if you can correctly diagnose the patient in this case study. Submit your answer to see if you were correct.

Tina Tan, MD, FAAP, FIDSA, FPIDS, tells Contemporary Pediatrics, “This is not new and demonstrates what is known, in that if vaccination rates do not stay at a level that is protective, outbreaks of vaccine preventable diseases will occur.”

The approval makes dupilumab the first and only treatment specifically indicated for eosinophilic esophagitis (EoE) patients aged 1 to 11 years that weigh at least 33 lbs (15 kg).

In 2021, current-use prevalence of cannabis was lower among male students compared to female students for the first time. This led investigators to conclude that developing interventions that consider protective factors by sex or gender could lead to equity in cannabis reduction strategies among youth.

“In pediatric patients, we know that there will be increased scar tissue formation, so it is even more necessary to prevent and reduce the residual burn scars,” Stan Monstrey, former secretary general, president, European Association of Plastic Surgeons, told Contemporary Pediatrics.

Decreasing severe adverse safety events (ASEs) could improve the poor outcomes associated with children with out-of-hospital cardiac arrest (OHCA), since 60% had at least 1 ASE.

Investigators of a new study published in JAMA Pediatrics concluded that maternal vaccination was safe with regard to neurodevelopment of the child at ages 12 months and 18 months.

Review some of the top stories from the Contemporary Pediatrics website over the last week, and catch up on anything you may have missed.

Though the association of BMI gain and 100% fruit juice in children was “small,” authors concluded their findings support public health guidance to limit consumption of the beverage to prevent overweight and obesity.

In this Contemporary Pediatrics interview, Ari Brown, MD, FAAP, details the benefits of goat milk-based infant formula, discusses FDA authorized Kabrita goat milk-based infant formula, and highlights misconceptions associated with goat milk-based formula.

Investigators of a study published in Annals of Internal Medicine concluded that the BNT162b2 COVID-19 vaccine demonstrated efficacy against the Delta and Omicron variants of COVID-19 in children and adolescents, offering new, extended follow-up period data.

In this Contemporary Pediatrics interview, Steven Selbst, MD, talks about how preventable unintentional firearm injuries in children can be, as he references an uptick in these cases in his emergency department.

Main factors contributing to the hospitalization of pediatric patients with influenza A were abdominal pain, viral co-infection and some hematological abnormalities.

According to new pooled individual patient responses, roflumilast cream 0.15% treatment led nearly 92% of individuals to achieve a measurable improvement in the Eczema Area and Severity Index.

“I think these injuries in particular are tragic, these unintentional ones, because they are preventable,” said Steven Selbst, MD. “If parents would lock the gun or keep the gun stored without the ammunition, it would be preventable, but parents don't do that.”

Seborrheic dermatitis patients with an inadequate response or intolerance to steroids were 3.5 times more likely to achieve Investigator Global Assessment (IGA) success with roflumilast foam 0.3% compared to vehicle, new data from the 2024 Winter Clinical Dermatology Conference revealed.

Review some of the top stories from the Contemporary Pediatrics website over the last week, and catch up on anything you may have missed.

Steven Selbst, MD, provides an update as to what he is seeing in the emergency department related to influenza, RSV, and COVID-19.

New interim data from the on-going, long-term extension ADORING 3 study and from an integrated analysis of the entire ADORING development program revealed efficacy and safety using tapinarof cream 1% continued beyond 8 weeks of treatment.

Compared to placebo, linaclotide demonstrated a statistically significant and clinically meaningful improvement in spontaneous bowel movement(s) (SBM) frequency rate, and was subsequently approved by the FDA in June 2023.

MediWound Ltd is seeking to expand the label for NexoBrid, already approved for eschar removal in adult patients, to the pediatric indication after the FDA accepted a supplemental Biologics Application for this patient population.

Though more research is needed to determine reasons for the association, a study published in JAMA Network revealed the 2021-2022 influenza season was associated with a significantly higher household transmission risk compared to pre-pandemic seasons.

The study authors noted that without video evidence, seizures would not have been implicated in death investigations and that seizure-related deaths are underrecognized in patients with epilepsy and in those without.

Marstacimab reduced the annualized bleeding rate (ABR) by 35% and nearly 92%, respectively, compared to routine prophylaxis and on-demand treatment in hemophilia A and B patients without inhibitors, according to Pfizer.

Berdazimer gel, 10.3% demonstrated positive, topline data in the phase 3 randomized clinical B-SIMPLE4 trial (NCT04535531) that featured a total of 891 patients aged 6 months or older who had 3 to 709 raised molluscum contagiosum lesions.

Review some of the top stories from the Contemporary Pediatrics website over the last week, and catch up on anything you may have missed.

Results demonstrated that caregiver burden scored a 2.14 on the caregiver burden scale, which is within the average burden level, though a higher burden of care is associated with a higher sense of loneliness. These results can help health care professionals develop a family-centered treatment plan.