FDA accepts application for VP-102 for treating molluscum contagiosum

Article

A new drug application for VP-102 for treating molluscum contagiosum has been accepted by the FDA.

The FDA has accepted a resubmitted new drug application (NDA) for VP-102 (YCANTH; Verrica Pharmaceuticals) for treating molluscum contagiosum, a skin disease commonly seen in young people.

About 6 million people in the United States experience molluscum contagiosum, with most cases being seen in children. The skin disease is highly contagious, leading to pain-causing lesions which can be skin-toned to pink-toned. These lesions also cause inflammation, itching, and bacterial infection.

Transmission of molluscum contagiosum is highly likely through fomites and direct skin-to-skin contact. The average case can last up to 13 months without treatment, with some lasting for multiple years. Currently, there are no FDA-approved treatments for molluscum.

VP-102 delivers cantharidin through a single-use applicator, leading to accurate dosing and targeted administration. The proprietary drug-device combination product could be the first approved by the FDA for treating molluscum contagiosum. Currently, it has completed a phase 2 study for treating common warts and a phase 2 study for treating external genital warts.

According to Ted White, president and chief executive officer of VerricaPharmaceuticals, VP-102 has shown strong safety and efficacy results for treating molluscum contagiosumin 2 phase 3 trials. July 23, 2023 is the Prescription Drug User Fee Act date currently set for the product.

"I am excited about the possibility of the Verrrica-102 cantharidin treatment for molluscum receiving approval," said Bernard Cohen, MD, professor of pediatrics and dermatology at Johns Hopkins University School of Medicine. "The company is 1 step closer, and we all await further consideration by the FDA."

Verrica Pharmaceuticals is a therapeutics company focused on dermatology. Medications developed by the company are for skin diseases which need medical interventions, with VP-102 being developed for 3 of the largest unmet needs in medical dermatology: common warts, external genital warts, and molluscum contagiosum.

Reference

Verrica Pharmaceuticals announces FDA acceptance of filing of resubmitted NDA for VP-102 for the treatment of molluscum contagiosum.BioSpace. February 27, 2023. Accessed February 28, 2023. https://www.biospace.com/article/releases/verrica-pharmaceuticals-announces-fda-acceptance-of-filing-of-resubmitted-nda-for-vp-102-for-the-treatment-of-molluscum-contagiosum/

Newsletter

Access practical, evidence-based guidance to support better care for our youngest patients. Join our email list for the latest clinical updates.

Recent Videos
Tina Tan, MD, comments on FDA expanded approval for MenQuadfi meningococcal disease vaccine
Jennifer Soung, MD reacts to FDA approval of roflumilast foam 0.3%
Suzanne Hollander, MS, RD, LDN, Senior Clinical Nutrition Specialist, Boston Children's Hospital | Image credit: Boston Children's
Russell Libby, MD, FAAP
Lawrence Eichenfield, MD
© 2025 MJH Life Sciences

All rights reserved.