New tools for children with Type 1 diabetes


Insulin analogs, advanced insulin pumps, and improved glucose monitoring devices make it easier to achieve glycemic control while decreasing the risk of hypoglycemia.

A little background

Pancreatic β-cells secrete insulin at a low basal rate that controls glucose levels in the fasting state; they also secrete increased amounts of insulin that control glucose levels after food intake. To normalize blood glucose levels in diabetics, administered insulin must replicate this endogenous basal-bolus pattern of insulin secretion.

Recombinant DNA technology allowed for structural modifications of insulin to alter its rate of absorption after subcutaneous injection. Thus, insulins could be designed with peaks and durations of action that would be better suited to provide either basal or bolus insulin needs.

Related Videos
Wendy Ripple, MD
Wendy Ripple, MD
Courtney Nelson, MD
DB-OTO improved hearing to normal in child with profound genetic deafness | Image Credit: © Marija - © Marija -
Carissa Baker-Smith
Perry Roy, MD
Perry Roy, MD | Image Credit: Carolina Attention Specialists
Angela Nash, PhD, APRN, CPNP-PC, PMHS | Image credit: UTHealth Houston
Allison Scott, DNP, CPNP-PC, IBCLC
© 2024 MJH Life Sciences

All rights reserved.