Infectious Diseases

AAP guidance expands RSV immunization eligibility for children aged 8 through 19 months at high risk of severe disease.

CDC has declared the Nara Organics infant botulism outbreak over; genetic testing ties it to the 2025 ByHeart outbreak.

Nine societies outline 6 domains of hospital-level sepsis strategies, from rapid blood culture diagnostics to daily toothbrushing protocols.

The AAP recommends annual flu vaccination for all children aged 6 months and older and updates antiviral guidance for the 2026–2027 season.

Infliximab or steroids may be more effective than anakinra as adjunctive therapy for children with MIS-C who do not respond to IVIG.

Starting antiviral therapy within 48 hours of influenza symptom onset was associated with an 81% lower hospitalization risk in children.

Navigate back-to-school vaccine requirements, evidence, and FAQs—plus the latest measles data and new pneumococcal options for pediatric practice.

Executive order seeks to trim routine childhood vaccines, split combination shots, and push parent-doctor decisions—sparking debate as measles surges.

FDA accepted Merck's sBLA extending ENFLONSIA (clesrovimab-cfor) to high-risk children under 2 in their second RSV season.

Ensitrelvir adds an FDA-approved COVID-19 postexposure prophylaxis option for adults and adolescents aged 12 years or older.

US measles cases have climbed to 2,318 in 2026, already exceeding all of 2025 and marking the country's highest annual total since 1991, as CDC data show falling MMR coverage continuing to fuel outbreaks.

The PECOS study found 20 post-COVID symptoms in children; Roberta L. DeBiasi, MD, discusses evaluation and follow-up.

Alesia McKeown, PhD, of Roche Diagnostics discusses why pertussis is missed in children and adolescents and how PCR testing can help.

With a multistate cyclosporiasis outbreak underway this summer, pediatric providers should maintain a low threshold to consider Cyclospora cayetanensis in children with protracted or relapsing watery diarrhea.

A 10-year King County study found MMRV was the first vaccine for 15% of children who were disproportionately Hispanic, Black, or VFC eligible.

A matched cohort study found no meaningful difference in serious or outpatient infection risk between infliximab and adalimumab in pediatric IBD.

FDA approved the first generic rifapentine for active and latent tuberculosis, expanding treatment options for eligible pediatric patients.

Baloxavir marboxil is a first-in-class cap-dependent endonuclease inhibitor that functions as a prodrug.

The approval is based on data from the phase 3 STRIDE-13 trial.

A CHOP-led study identified IL-6 and IFN-γ immune activation tied to worse recovery in children with sepsis or organ failure.

The FDA has approved expanded indications for tocilizumab-bavi (TOFIDENCE), adding severe or life-threatening CAR T-cell–induced CRS and hospitalized COVID-19 in patients aged 2 years and older.

New research using a natural experiment design found consistent reductions in diagnosed influenza among vaccinated young children in every season studied from 2016 to 2023.

Common pediatric skin infections are often managed in primary care, but some presentations require dermatology referral and further evaluation.

FDA approved ensitrelvir for COVID-19 post-exposure prophylaxis in patients aged 12 years and older after positive phase 3 trial results.

French data suggest dual RSV immunization with RSVpreF and nirsevimab was associated with low infant RSV hospitalization rates.