Weekly review: AAP immunization schedule, vatiquinone CRL, and more
Get caught up with Contemporary Pediatrics! This list helps you navigate our top stories from the week, all in one place.
FDA approves first RNA-targeted therapy for hereditary angioedema
In recent studies, donidalorsen (DAWNZERA) has demonstrated durable efficacy and long-term disease control.
How effective is tacrolimus therapy in juvenile myasthenia gravis?
Tacrolimus shows promise in treating juvenile myasthenia gravis, improving symptoms with minimal adverse effects, suggesting a valuable second-line therapy option.
Low-dose steroid effective for severe pediatric Mycoplasma pneumoniae pneumonia
Low-dose methylprednisolone is as effective as high-dose for severe pediatric MPP and has fewer side effects, supporting safer treatment strategies.
Study links pediatric EoE treatment to reduced stiffening
Controlling childhood EoE inflammation improves esophageal flexibility, reduces dysphagia risk, and may predict need for stricture dilation.
Teens with CHD are less likely than peers to receive contraception
Young females with congenital heart disease face barriers to contraception, increasing their risk during pregnancy despite rising usage over time.
Centanafadine shows efficacy and tolerability for pediatric ADHD in phase 3 trial
High-dose centanafadine significantly improved ADHD symptoms in children aged 6–12 and was well tolerated, according to a phase 3 clinical trial.
HPV screening, vaccination accelerate cervical cancer decline
Biennial HPV testing and higher vaccination rates could help South Korea eliminate cervical cancer up to a decade earlier than current policy.
AAP updates guidance on iatrogenic opioid dependence and withdrawal in children
AAP updates guidance on recognizing and managing iatrogenic opioid dependence and withdrawal in children prescribed opioids.
Full case: A newborn baby with a rash
The baby had mild respiratory distress after delivery and briefly required supplemental oxygen via blow by during transitioning.
Breastfeeding in first 4 to 6 months of life is linked to lower central precocious puberty risk
Investigators noted the association was partially mediated by prepubertal adiposity.
FDA issues CRL for vatiquinone to treat Friedreich ataxia
If approved, vatiquinone would have been the first therapy approved for pediatric patients with FA.
American Academy of Pediatrics releases immunization schedule
The AAP recommends that all children aged 6 months to 23 months receive a COVID-19 vaccine, as this group is the highest risk for severe infection.
Can you diagnose this rash in a newborn?
What's the diagnosis?
AAP policy: Developing trauma systems that provide optimal care
The AAP stated public health and trauma care should address "needs of injured children across the continuum of care."
Michael Haller, MD, discusses safety and use for inhaled insulin in T1D
Michael Haller, MD, discusses inhaled insulin’s safety, off-label use, and future role in easing type 1 diabetes management for children.
FDA approvals for NCFB, CKD; adolescent vaccine coverage; and more
Get caught up with Contemporary Pediatrics! This list helps you navigate our top stories from the week, all in 1 place.
School avoidance linked to emotional distress in children, survey finds
Survey finds 30% of children missing school due to anxiety miss over a week; experts urge early intervention and therapy to address school avoidance.
Managing mental health between specialist visits with Elizabeth Reichert, PhD
Psychologist Elizabeth Reichert, PhD, encourages primary care providers to use validation and connection to support mental health during routine visits.
Adolescent vaccination coverage improves for Tdap and MenACWY; HPV rates remain unchanged
Among adolescents aged 13 to 17 years, coverage with 1 or more Tdap dose increased from 89% to 91.3% from 2023 to 2024, respectfully.
Richard Auchus, MD, on how crinecerfont is changing CAH treatment
Richard Auchus, MD, PhD, discusses how crinecerfont is improving CAH care and easing the transition from pediatric to adult management.
Higher vitamin D levels in early pregnancy linked to improved child cognition
Higher maternal vitamin D in early pregnancy linked to better fluid and overall cognition in children, especially among those of Black mothers.
Adolescents spend nearly one hour per school day on smartphones
Results revealed students aged 10 to 13 years spent over 45 minutes on social media apps during school hours.
Respiratory target linked to successful lung aeration during preterm neonate resuscitation
A minimum expiratory tidal volume of 4 mL/kg is associated with successful lung aeration during delivery room resuscitation of preterm neonates.
Sports nutrition 101: What young athletes should eat and drink
Discover essential nutrition tips for young athletes to enhance performance, hydration, and recovery before, during, and after sports activities.
FDA approves first generic iron sucrose injection for iron deficiency anemia in CKD
FDA approves first generic iron sucrose injection for treating iron deficiency anemia in CKD patients 2 years and older.
FDA approves brensocatib to treat adolescents with non–cystic fibrosis bronchiectasis
Brensocatib was granted FDA priority review in February 2025 for the small molecule, oral, reversible inhibitor.
FDA accepts priority review for gepotidacin as oral treatment for gonorrhea
FDA accepts priority review of gepotidacin, a first-in-class oral antibiotic, for treating uncomplicated urogenital gonorrhea in patients ≥12 years.
A brief review of primary care resources and toolkits for the stimulant shortage
Explore essential resources and toolkits for managing the ongoing stimulant medication shortage affecting ADHD treatment and patient care.
Aleece Fosnight, PA-C, discusses bladder control issues and associations with food
Hydration, timed voiding, and limiting bladder-irritating foods can help kids manage incontinence, says Aleece Fosnight, PA-C, in this Q+A interview.
