How could NexoBrid change the pediatric thermal burn treatment landscape?
“In pediatric patients, we know that there will be increased scar tissue formation, so it is even more necessary to prevent and reduce the residual burn scars,” Stan Monstrey, former secretary general, president, European Association of Plastic Surgeons, told Contemporary Pediatrics.
Study finds buprenorphine reduces congenital malformation risk in infants
A recent study revealed that infants exposed to buprenorphine during the first trimester exhibit a significantly decreased risk of developing congenital malformations associated with opioid exposure compared to infants exposed to methadone.
Over half of children with out-of-hospital cardiac arrest experience 1 adverse safety event
Decreasing severe adverse safety events (ASEs) could improve the poor outcomes associated with children with out-of-hospital cardiac arrest (OHCA), since 60% had at least 1 ASE.
USPSTF: Speech, Language Delay Screening Lacks Evidence in Young Children
A new recommendation statement from the Preventive Services Task Force remains inconclusive on the benefits versus risks of asymptomatic screening for speech and language delay disorders.
If AI isn’t ready to diagnose patients, where can it be used in health care?
Considering AI’s potential limitations in diagnosing patients or designing treatment plans, it’s understandable that physicians and other medical professionals would prefer to keep its clinical use at arm’s length for the time being.
COVID-19 vaccination during pregnancy and offspring neurodevelopment
Investigators of a new study published in JAMA Pediatrics concluded that maternal vaccination was safe with regard to neurodevelopment of the child at ages 12 months and 18 months.
Green space could reduce risk of childhood myopia development
A recent cohort study in China reports suggests the structure of green space decreased the relative risk of myopia among school-aged children.
Contemporary Pediatrics week in review: Roflumilast foam data, accidental firearm deaths in children, and more
Review some of the top stories from the Contemporary Pediatrics website over the last week, and catch up on anything you may have missed.
Increased servings of 100% fruit juice per day associated with BMI gain in children
Though the association of BMI gain and 100% fruit juice in children was “small,” authors concluded their findings support public health guidance to limit consumption of the beverage to prevent overweight and obesity.
11-year-old boy with testicular pain and rash
An 11-year-old boy presented to the emergency department complaining of left testicular pain for 2 days, described as intermittent and stabbing, which ranged between 5 and 8 of 10 in intensity. Read the full case to see if you can correctly diagnose the patient.
RSV poses higher hospitalization risk in children than influenza or Omicron
A new study shows that, among the tridemic viruses, RSV was the leading cause of pediatric hospitalizations.
Goat milk-based infant formula: Benefits, data, and misconceptions
In this Contemporary Pediatrics interview, Ari Brown, MD, FAAP, details the benefits of goat milk-based infant formula, discusses FDA authorized Kabrita goat milk-based infant formula, and highlights misconceptions associated with goat milk-based formula.
Research exposes inequalities in breastfeeding assistance for individuals with disabilities
A recent study using the Pregnancy Risk Assessment Monitoring System highlighted lower rates of breastfeeding initiation and duration among women with disabilities, emphasizing the need for targeted interventions to improve breastfeeding outcomes.
BNT162b2 COVID vaccine effective in children amid Delta, Omicron periods
Investigators of a study published in Annals of Internal Medicine concluded that the BNT162b2 COVID-19 vaccine demonstrated efficacy against the Delta and Omicron variants of COVID-19 in children and adolescents, offering new, extended follow-up period data.
Discussing unintentional firearm injuries among children, and how preventable they can be
In this Contemporary Pediatrics interview, Steven Selbst, MD, talks about how preventable unintentional firearm injuries in children can be, as he references an uptick in these cases in his emergency department.
2024 to become ‘Super Bowl’ of telehealth regulation, trade group says
ATA publishes 2024 policy agenda after solid year of advocacy in 2023.
Clinical characteristics of pediatric influenza hospitalization
Main factors contributing to the hospitalization of pediatric patients with influenza A were abdominal pain, viral co-infection and some hematological abnormalities.
Roflumilast cream 0.15% for atopic dermatitis demonstrates strong individual patient response data
According to new pooled individual patient responses, roflumilast cream 0.15% treatment led nearly 92% of individuals to achieve a measurable improvement in the Eczema Area and Severity Index.
CDC: Unlocked, loaded firearms significantly contribute to accidental firearm deaths in children
“I think these injuries in particular are tragic, these unintentional ones, because they are preventable,” said Steven Selbst, MD. “If parents would lock the gun or keep the gun stored without the ammunition, it would be preventable, but parents don't do that.”
Roflumilast foam, 0.3% effective in seb patients with intolerance to steroids
Seborrheic dermatitis patients with an inadequate response or intolerance to steroids were 3.5 times more likely to achieve Investigator Global Assessment (IGA) success with roflumilast foam 0.3% compared to vehicle, new data from the 2024 Winter Clinical Dermatology Conference revealed.
Low probability of developing long COVID in children
While the study detected a rise in chronic symptoms among children who developed post-COVID-19 condition, the likelihood of initial development was minimal.
Contemporary Pediatrics week in review: New topline data for tapinarof cream and linaclotide
Respiratory ED update: Influenza, RSV, and COVID-19
Steven Selbst, MD, provides an update as to what he is seeing in the emergency department related to influenza, RSV, and COVID-19.
Maternal type 1 diabetes increases congenital heart defect risk in children
A new study identified type 1 diabetes (T1D) as a risk factor associated with nearly all subtypes of CHD, whereas overweight was associated only with certain defect types.
New topline phase 3 data for tapinarof cream 1% to treat AD in children
New interim data from the on-going, long-term extension ADORING 3 study and from an integrated analysis of the entire ADORING development program revealed efficacy and safety using tapinarof cream 1% continued beyond 8 weeks of treatment.
Pfizer COVID-19 vaccine significantly protected children, adolescents during pandemic
The estimated efficacy of the vaccine against documented infection for children and adolescents during the Omicron wave was 74.3% and 85.5%, respectively.
RSV this year: Clinician insights and urgent vaccination strategies
In a recent panel, clinicians discussed rising cases of respiratory syncytial virus (RSV), vaccination challenges, and the urgent need for public awareness and intervention strategies in the 2023 to 2024 season.
Safety and efficacy of FDA-approved linaclotide reinforced with new phase 3 data
Compared to placebo, linaclotide demonstrated a statistically significant and clinically meaningful improvement in spontaneous bowel movement(s) (SBM) frequency rate, and was subsequently approved by the FDA in June 2023.
FDA accepts sBLA for NexoBrid to remove eschar in pediatric thermal burn patients
MediWound Ltd is seeking to expand the label for NexoBrid, already approved for eschar removal in adult patients, to the pediatric indication after the FDA accepted a supplemental Biologics Application for this patient population.
Maternal folic acid linked to reduced Kawasaki disease risk in infants
A study revealed that higher maternal folic acid levels and frequent supplementation during pregnancy can significantly lower the risk of Kawasaki disease in infants, highlighting the potential protective role of folic acid.
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