Gastroenterology

TNX-2900 was previously granted Orphan Drug designation by the federal agency in 2022 for the treatment of PWS.

Gluten-free meal plans can be a critical treatment option and necessity for those with celiac disease. But for children with no medical conditions or restrictions? A gluten-free diet should not be the mainstay diet.

The approval makes dupilumab the first and only treatment specifically indicated for eosinophilic esophagitis (EoE) patients aged 1 to 11 years that weigh at least 33 lbs (15 kg).

Though the association of BMI gain and 100% fruit juice in children was “small,” authors concluded their findings support public health guidance to limit consumption of the beverage to prevent overweight and obesity.

Compared to placebo, linaclotide demonstrated a statistically significant and clinically meaningful improvement in spontaneous bowel movement(s) (SBM) frequency rate, and was subsequently approved by the FDA in June 2023.

The United States Preventive Services Task Force (USPSTF) is planning to recommend that comprehensive, intensive behavioral interventions be the primary effective intervention for weight loss in children and adolescents with high body mass indexes (BMI).

Data from a 4-year trial of preschool-aged children offers new insight into the effects of initiating obesity management strategies among children in early life.

Watch as Rob Knight, PhD, Wolfe Endowed Chair in Microbiome Science at Rady Children's Hospital-San Diego, professor of pediatrics, UCSD, talks the gut microbiome and the potential associations with cognitive and neurological conditions in children, and why the topic is gaining interest and momentum.

Investigators concluded that clinicians should be aware, for individuals with a prior rotavirus-associated hospitalization, of an elevated susceptibility to autoimmune disease in these patients. 

To combat this association, study investigators concluded a reduction in daily soft drink consumption should be a priority among school-going adolescents.

This recent research indicates the necessity for clinicians to be aware of the higher autoimmune disease susceptibility of those with previous rotavirus-associated hospitalization.

A new scientific statement indicates lifestyle interventions may change the trajectory of obesity-related cardiovascular risk from onset in childhood to manifestation in adulthood.

GLP-1 receptor agonists, used to treat diabetes, are now also being used for obesity in children and adolescents.

An analysis of data from nearly 750,000 adolescents from more than 40 countries offers insight into the changing, and possibly inaccurate, perceptions of healthy body weight among younger people since the turn of the century.

Nicole Peña Sahdala, MD, internist, gastroenterologist specialist in bariatric endoscopy, ABIM certified, discusses the rise in bariatric surgery among youth, and why other forms of care, such as lifestyle changes and education, are essential before any surgery is performed.

Links between teenager anxiety and gastrointestinal (GI) issues are the subject of this Contemporary Pediatrics® interview with Julia Anderson, MD, MSCI; and Sara Francis, PhD.

Based on results from a recent C.S. Mott Children’s Hospital National Poll on Children’s Health, find out how comfortable parents feel when it comes to abdominal pain in their child, and how likely they are to handle the issue themselves, or to reach out to a health care provider for help.

The American Medical Association is asking doctors to scale back the use of the body mass index (BMI) when assessing obesity and health in patients, noting it should be used jointly with other measurements, and not solely. 

Kirk Thame, MD, associate professor, pediatric gastroenterology, hepatology, and nutrition, Monroe Carell Jr. Children’s Hospital at Vanderbilt, Nashville, Tennessee, explains how linaclotide differs from other treatment options for pediatric functional constipation, and why children will benefit from its recent FDA approval.

This decision marks the first functional constipation treatment approved by the FDA for this patient population.

Providers who refer patients for clinical hypnosis must ensure that the chosen hypnotherapist has appropriate knowledge about the patient’s gastrointestinal condition and has conducted clinical hypnosis for it.

A new analysis found differences in the gut bacteria seen in adults with obesity, suggesting that changes in the gut microbiota that predispose to adult obesity may begin in early childhood.

Erica Gunderson, PhD, MS, MPH, RD, senior research scientist, Kaiser Permanente Northern California Division of Research, professor of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine discusses how cardiometabolic health and childhood obesity are linked to breastfeeding. Gunderson also discusses receiving the 2022-2023 March of Dimes Agnes Higgins Award at the Pediatric Academic Societies meeting in Washington, DC on April 30, 2023.

In addition, 17 female patients who completed PENFS showed improvements in various symptoms, such as pain, disability, and catastrophizing, while carbohydrate degradation and LCFA synthesis pathways decreased in the post-treatment and follow-up analysis.

In a recent study, children of women in an IR-hyperglycemic group were 5 times more likely to develop childhood obesity than those from a control group.