Neonatal/Perinatology

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Infants born to mothers who receive vitamin D supplementation while pregnant are at reduced risk of being small for gestational age and experience improved growth during infancy, with no increased risk of fetal or neonatal mortality and congenital malformation. These were major findings of a systematic review and meta-analysis of 24 randomized controlled trials involving 5405 participants.

A 33-year-old female, G3P1011, was transferred from an outside facility at 33 weeks and 6 days gestation for anticipated preterm delivery secondary to preeclampsia. On prenatal ultrasound, her fetus was diagnosed with an omphalocele and delivery was preferred at an institution with a neonatal intensive care unit to manage the infant.

Investigators compared the accuracy of an American Academy of Pediatrics (AAP) practice guideline algorithm for diagnosing of urinary tract infection (UTI) in 2- to 23-month-olds with a new tool (UTICalc; University of Pittsburgh, Pennsylvania) that first estimates UTI probability based on clinical variables and then, if laboratory testing is performed, updates the estimate based on the results.

A meta-analysis of 12 studies of the risk of death after a brief resolved unexplained event (BRUE) found that such an event does not increase an infant’s risk of dying during his or her first year. The American Academy of Pediatrics (AAP) introduced BRUE, a sudden alteration in an infant’s breathing, color, tone, or responsiveness, as a replacement for “apparent life-threatening event” (ALTE) in a 2016 clinical practice guideline.