Allergy, Immunology, and ENT

The Fast Track Designation follows the recent announcement of phase 1/2 data from the Harmony trial.

This research highlights the close relationship between pollen-induced allergic rhinitis, sensitization, and asthma.

S salivarius probiotic reduces relative abundance of nasopharyngeal otopathogens but not incidence of acute otitis media in children.

At the 2023 American Academy of Pediatrics National Conference & Exhibition, Paul V. Williams, MD, FAAP, explains his session "Tell Me it Ain't So: Delabeling Penicillin Allergy," and how general pediatricians can make a difference by removing a false penicillin allergy label from a child's medical record.

Desensitization was observed in children aged 1 to 4 years using peanut sublingual immunotherapy (SLIT) compared to placebo, demonstrating a significantly greater median cumulative tolerated dose and higher likelihood of demonstrating remission.

This new data is consistent with previous results on efficacy and on safety shown in global phase 3 studies that had enrolled both adults and adolescents.

Regeneron states all 10 patients achieved normalization of serum albumin and serum IgG concentrations by week 12 in a phase 2/3 trial that investigated the safety and efficacy of pozelimab-bbfg. These concentrations were maintained through 72 weeks.

This expanded upon the limited data available on risks of precautionary allergen label food introduction for those with allergies, the results of which suggest new possibilities for future allergy management.

New data on oral immunotherapy to food allergens shows promise for the treatment, though more information with standard interventions and regimens is needed to gain certainty on the efficacy and safety.

A new study investigates taking this treatment a step further, evaluating the effect of epicutaneous immunotherapy in toddlers with known peanut allergies.

The FDA recently approved Hyqvia, expanding its use to treat pediatric patients with primary immunodeficiency (PI) aged 2 to 16 years.

In a recent study, penicillin allergy documentation was uninformative in allergy tabs, and children were not often referred to allergists.

Recent data, presented at the AAAAI annual meeting, showed that oral sesame desensitization through crushed seeds and tahini was efficacious and safe for pediatric patients.

New data presented at ACAAI 2022 observed various trends in allergies associated with eczema and eosinophilic esophagitis, comparing observed data with that of patients in the United States.

A recent study in Finland finds 2 major contributing factors to allergic disease in infants with familial risk.

Research by Ben Katz, MD, and other investigators has brought new insight on chronic granulomatous disease to light.

The US Food and Drug Administration (FDA) Vaccines and Related Biological Products Advisory Committee unanimously voted recently to recommend both the Pfizer-BioNTech and Moderna COVID-19 vaccines for individuals aged 6 months and older.

Study links inappropriate, off-guideline antibiotics to increased, avoidable allergic and adverse events in children.

Asthma may increase patient risk of developing dry eye disease.

Experts note that, with cow’s milk allergies seemingly on the rise, pediatric health care providers can help parents be vigilant.

Two twin brothers with a rare disorder get both their dreams realized-a super cool playset and a trip to the happiest place on earth.

Peanut oral immunotherapy has been beneficial to children with peanut allergies. A new study looks at just how effective it is.

Parents may be turning to formula made in the home or imported from Europe to help with their child's food allergies, but there are a number of concerns.

At the virtual 2021 American Academy of Pediatrics National Conference & Exhibition, Vivian Hernandez-Trujillo, MD, FAAP, FAAAAI, FACAAI, division director, Allergy and Immunology, and fellowship training program director, Allergy and Immunology at Nicklaus Children’s Hospital in Miami, Florida presents a session on best practices for preventing food allergies in newborns and infants.

A new study offers insight into what early-life risk factors can help predict future nut allergies.