Allergy, Immunology, and ENT

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child holding peanuts

Peanut allergies often elicit frightening reactions in children. The new drug Palforzia, just approved by the US Food and Drug Administration (FDA), can reduce the risk of a child having that potentially life-threatening reaction.

girl with peanuts

Food allergies are a hot topic on the playground, at schools, and in pediatric offices. Parents of children with eczema or atopic dermatitis (AD) often have a lot of questions regarding the connection between eczema, exposure to common food allergens, and the development of or exacerbation of AD. There are many of the complex questions that clinicians must answer when evaluating pediatric patients with AD.

image illustrating common and serious food allergen

Dr. Todd A. Mahr, president of the American College of Allergy, Asthma, and Immunology, discusses anaphylaxis and when to have your patient seek specialty care. Anaphylaxis is typically thought of as severe, acute and visibly evident. However, as Dr. Mahr points out, anaphylaxis can present differently in infants and young children.

A 4-year-old, previously healthy girl presented to a tertiary care children’s hospital emergency department (ED) with large, tense bullae involving up to 40% of her body surface area. The patient’s parents described a 12-day history of itchy, papulovesicular lesions that had progressed into large blisters.

As the calendar advances to the fall months, we are reminded everywhere that it’s time for the annual influenza vaccination. In August 2011, the Advisory Committee on Immunization Practices (ACIP) updated its vaccination recommendations to include new guidelines for children ages 6 months through 8 years, and for persons with egg allergy.

Lessons From Colby

Like many physicians, I find it difficult to care for a patient with a terminal disease-a discomfort heightened when the patient is an ebullient, beautiful child.

This 9–month–old boy was initially evaluated at age 6 weeks for an extensive eczematous rash on the head and antecubital and diaper areas and blood and mucus in the stool with each diaper change over a 2– to 3–week period. The symptoms were attributed to milk allergy, and the infant’s formula was changed. At 8 weeks of age, a petechial rash developed on the boy’s trunk and legs. His symptoms persisted despite multiple formula changes, and he was referred to the emergency department.

A 7-month-old boy with a history of severe atopic dermatitis and asthma was brought for evaluation of a generalized rash, fever, and irritability of 2 days’ duration. He had no respiratory symptoms. His medical history was significant for anorexia, without vomiting or diarrhea. He had a strong family history of allergy.

At his first well-child visit after a family move, an 8-year-old boy was noted to have bilateral erythematous plaques on the surfaces of his hands and feet. Mother reported that the condition had been present since he was 2 or 3 months old. Patient’s father and other male relatives on the paternal side (uncles, grandfather, great-grandfather) were similarly affected. No other associated symptoms, such as hyperhidrosis, reported. The child did not have a history of eczema, asthma, or food allergies; however, he did have a history of allergic rhinitis and occasional pruritus.

“Drug rash” is a common pediatric complaint in both inpatient and outpatient settings. This term, however, denotes a clinical category and is not a precise diagnosis. Proper identification and classification of drug eruptions in children are important for determining the possibility of-and preventing progression to-internal involvement. Accurate identification is also important so that patients and their parents can be counseled to avoid future problematic drug exposures.