October 8th 2025
The BeeLine trial is a placebo-controlled study designed to evaluate radiprodil’s impact on both seizure frequency and non-seizure symptoms associated with GRIN-NDD.
Zika may have led to negative outcomes in kids born with normal head size
July 16th 2020Parents of newborns who had been exposed to Zika virus in utero may have breathed a sigh of relief when their child was born with normocephaly. An investigation finds that adverse outcomes occurred even in children with normal head size.
Fenfluramine may be a new treatment option for Dravet syndrome
March 11th 2020When added to existing antiepileptic treatment, fenfluramine hydrochloride significantly reduced the frequency of convulsive seizures in children and young adults with Dravet syndrome and had a dose-response effect, according to a randomized trial in patients in whom seizures had not been completely controlled by their current treatment regimen.
8 questions for a thorough history to diagnose migraines
January 22nd 2020When evaluating and diagnosing migraines in pediatric patients, a thorough medical history is key to giving a diagnosis. These 8 questions are structured to pinpoint concerning headache patterns earlier in the diagnosing process.
Using fast MRI to assess brain injuries
September 25th 2019Computed tomography scans are often used when treating children for traumatic brain injury, but the exposure to ionizing radiation may give a clinician pause in cases that are extremely subtle. A new study published in Pediatrics looked at whether fast magnetic resonance imaging (MRI) scans, meaning motion-tolerant MRI sequences done without sedation) was accurate and feasible in young children.
How a web-based model helps predict epilepsy risk
January 2nd 2019Not all children who have seizures are diagnosed with epilepsy, and a definitive diagnosis can be difficult to make. Now, researchers from the Netherlands have developed a Web-based tool to help clinicians predict the probability of future seizures based on early clinical data.
Impact of rapid treatment for pediatric status epilepticus (VIDEO)
February 9th 2018For Contemporary Pediatrics, Dr Bobby Lazzara discusses a multicenter observational study published in JAMA Neurology that looked at time to treatment in children with refractory convulsive status epilepticus and the impact on mortality.