At AAP 2026, Justin Wheeler, MD, discussed bowel cleanouts, maintenance therapy, and behavioral strategies for managing constipation in children.

Justin Wheeler, MD, explains how pediatricians can identify constipation across age groups and distinguish overflow incontinence from diarrhea.

Mark R. Corkins, MD, CNSC, FASPEN, AGAF, FAAP, reviews where pediatric probiotic evidence is strongest, why product quality varies, and which children should avoid them.

At AAP 2026, Carmen Tong, DO, discussed evaluating pediatric urinary symptoms and why behavioral strategies often come before medication.

In a 48-patient phase 1b trial, ecnoglutide was well tolerated in adolescents with obesity and reduced BMI up to 12.6% at 20 weeks.

In a Hirschsprung disease mouse model, diet shifted gut microbes and inflammation, with a 3-fold survival difference between standard diets.

A national claims analysis found 16.8% of pediatric GLP-1 users developed a nutritional deficiency within a year, most often vitamin D, while few received nutritional counseling.

Phase 3 CROSSING trial data show tezepelumab improved histologic remission and dysphagia versus placebo through week 52 in EoE.