Skin Diseases

New 16-week data from the SPROUT trial show the PDE4 inhibitor may be highly efficacious in children and adolescents.

This case study analyzes variants of majocchi granuloma and potential treatment.

A review examined the ways in which costs can be reduced for patients with varying types of atopic dermatitis.

In 2 recent phase 3 trials, safety and efficacy was proven in the use of roflumilast cream 0.3% for the treatment of plaque psoriasis.

Investigators suggest parents and clinicians should be mindful of children with suspected ACD with a history of exposure to jewelry, clothing, and belts with cobalt.

The US Food and Drug Administration has approved halobetasol propionate foam, 0.05%, a potent topical corticosteroid, for the treatment of plaque psoriasis in adolescent patients.

A healthy 9-day-old girl presents with erosions near her eyes, nose, and skin creases on the arm as well as a positive Nikolsky sign. What's the diagnosis?

Regeneron Pharmaceuticals, Inc. and Sanofi announced safety and efficacy results from LIBERTY AD trial for pediatric patients ages 6 months to 5 years.

A 12-year-old boy has had this brown patch on his left buttock since birth. His mother is concerned that the patch has grown over the years and she wants to be sure that it will not be a health concern for her son.

A 2-month-old infant had right submandibular swelling with inflammation and induration up to the nape of neck. Ultrasonography showed multiple enlarged lymph nodes with soft tissue swelling. Blood cultures grew Gram-positive cocci, which were identified as group B streptococci. Late-onset GBS infection is acquired from colonized household contacts.

Test your skills in this 5-question quiz.QUESTION 1: A 16-year-old boy presented with an extremely pruritic rash on the elbows, at the wrists, and on the top of the hands. This is classic for granuloma annulare.  Courtesy of Ted Rosen, MD

This annular configuration is classic for granuloma annulare; very widespread lesions may signal diabetes mellitus.

A 6-month-old girl was brought to the ED with fever, cough, and irritability; she appeared well-hydrated. She was born prematurely and had a long, complicated stay in NICU, where she received CPR on 2 occasions. There was concern about lung "congestion." The ED physician made a diagnosis of pneumonia. Rib fractures were also noted, but there was no history of fractures at the time of discharge from the NICU.

Acrodermatitis enteropathica and Langerhans cell histocytosis are recalcitrant forms of diaper dermatitis( DD); other variants are: candidal DD, irritant or contact DD, Jacquet’s disease, and psoriasis.

Take this week's quiz and test your diagnostic and therapeutic skills.

Take this week's quiz and test your diagnostic and therapeutic skills.

The morphology and distribution of these lesions is characteristic of ectoparasite bites, which occur when a human carries a pet-usually a kitten or puppy-as if the animal were a human newborn baby.

The black, hard center represents an eschar. This type of morphology is almost always caused by a virulent organism-bacterial or fungal. Biopsy showed non-septate hyphae within the dermis, and a culture grew Mucor species (a saprophytic soil fungus).

Bell palsy is a facial nerve palsy thought to be the result of a lower motor neuron lesion caused by an autoimmune response. Viral infections are commonly implicated.

This child's mother was worried that these lesions were sexually transmitted. What's your suspicion?

The mother of this 4-year-old girl was concerned that these lesions were sexually transmitted. The physician recognized them as molluscum, but was uncertain of the potential relationship of this rash to child abuse.

Acute hemorrhagic edema of infancy is a relatively uncommon form of leukocytoclastic vasculitis. Henoch-Schönlein purpura is the primary differential diagnosis.

In this 10 minute video, Dr. Ted Rosen addresses the following questions. A brief synopsis of Dr. Rosen’s comments follows.

A Hill-Sachs deformity is a compression injury to the posterolateral aspect of the humeral head created by the glenoid rim during dislocation.

The multiple erosions on this teenager's lip are most likely an exaggerated version of herpes labialis related to his underlying lymphoma. A viral culture would be useful to verify the diagnosis.

What's your diagnosis? More details here...

These circumferential symmetric skin creases are called the “Michelin Tire baby syndrome” because of their striking resemblance to the mascot of the French tire manufacturer.

Diaper Dermatitis is the most common skin problem in infants. The differential includes contact and seborrheic dermatitis, psoriasis, scabies, and infection. Treatment guidelines are outlined here.

The “rash” of innumerable asymptomatic flat-topped papules on this teenager’s face is highly likely to be flat warts.

Childhood absence epilepsy is distinct from partial epilepsy and is often misdiagnosed as ADD/ADHD. It is one of the most common types of pediatric seizure.