Childhood Immunization Rates in Britain Could Be Better
February 29th 2008Although the majority of British children are immunized with the combined measles, mumps and rubella (MMR) vaccine, a substantial proportion remain susceptible to infection due to the conscious decision of their parents not have them immunized, according to an article published Feb. 28 in BMJ Online First.
Obese Hispanic Adolescents Have Subclinical Inflammation
February 28th 2008Overweight Hispanic children and adolescents with normal glucose tolerance have higher levels of plasma markers of endothelial dysfunction and inflammation as well as high blood pressure, high triglycerides and insulin resistance, researchers report in the March issue of Diabetes Care.
Cystic Fibrosis Incidence Decreasing in Massachusetts
February 27th 2008Fewer newborns are being born with cystic fibrosis in Massachusetts, a decrease that researchers attribute to increased preconception and prenatal screening for the genetic disease, according to an article published in the Feb. 28 issue of the New England Journal of Medicine.
Obese Children More Likely to Have Anesthesia Trouble
February 27th 2008Anesthesia providers should be aware of perioperative complications that are more likely to occur with children who are obese, including major oxygen desaturation and critical airway events, according to research published in the March issue of Anesthesiology.
Ciprofloxacin-Resistant Meningitis Identified
February 27th 2008The first reported North American cluster of ciprofloxacin-resistant meningoccocal disease occurred in 2007-2008 in North Dakota and Minnesota, according to a report published in the Feb. 22 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.
SSRI-Resistant Teens Helped By Change in Regimen
February 26th 2008Chronically depressed adolescents who fail to respond to a first selective serotonin reuptake inhibitor (SSRI) may be successfully treated with cognitive behavioral therapy and a switch in antidepressant medication, a combination that appears to be more efficacious than switching medications alone, researchers report in the Feb. 27 issue of the Journal of the American Medical Association.
High Risk of Leukemia in Rare Immune Disorder Elucidated
February 25th 2008Nearly half of patients with severe congenital neutropenia, a rare genetic disorder, possess mutations in the gene encoding granulocyte colony-stimulating factor receptor, and new research elucidates how stem cells bearing this mutation gain clonal advantage over other bone marrow cells, leading to leukemia, according to an article published online Feb. 21 in the Journal of Clinical Investigation.
Gene Interaction Implicated in Cystic Fibrosis Severity
February 25th 2008Low expression of the mannose-binding lectin 2 (MBL2) gene appears to increase cystic fibrosis severity in part due to its association with Pseudomonas aeruginosa infection at a younger age, and MBL2's effects are increased in patients with a high-producing genotype of transforming growth factor beta 1 (TGFB1), according to a report published online Feb. 21 in the Journal of Clinical Investigation.
Sub-Saharan Africa's Brain Drain Called Crime
February 22nd 2008The active recruitment of health care workers from Sub-Saharan Africa is a violation of the human rights of African people and should be viewed as an international crime, according to an article in the Feb. 23 issue of The Lancet, which is a special issue on human resources for health.
Salty Foods Linked to Soft Drink Consumption in Children
February 21st 2008In children and adolescents, salt intake is strongly associated with total fluid and sugar-sweetened soft drink consumption, which supports public-health measures to limit salt content in foods, researchers report in the March issue of Hypertension.
Lack of Maternal Death Autopsy Data in Developing World
February 21st 2008In developing countries, the cause of maternal death is rarely investigated by autopsy, making it impossible to estimate the indirect causes and therefore make informed decisions on the best use of resources targeted at reducing maternal mortality, according to an editorial published in the February issue of PLoS Medicine.
Depression Symptoms Cured at Different Rates
February 21st 2008Antidepressant medications can improve a range of depression-related symptoms, but not all of the effects of depression subside at the same rate, according to a report published in the January/February issue of General Hospital Psychiatry.
Mass Antibiotics Can Eliminate Infectious Trachoma
February 19th 2008In rural Ethiopian villages severely affected by ocular chlamydial infections that cause trachoma, mass antibiotic distribution can eliminate the infections. But biannual distribution may be the most effective strategy, according to the results of a study published in the Feb. 20 issue of the Journal of the American Medical Association.