FAQ: Which children with early puberty actually need testing and treatment?
A new Endocrine Society guideline suggests watchful waiting rather than immediate testing for many girls with early breast development, reserving full evaluation for those with rapid progression or growth acceleration.
The Endocrine Society has released a new clinical practice guideline addressing the diagnosis and management of central precocious puberty (CPP), offering clinicians updated, evidence-based direction on when evaluation and treatment are warranted and when watchful waiting may be more appropriate.¹ The guideline was developed by a multidisciplinary panel using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach to address 10 priority clinical questions, and it is co-sponsored by the American Academy of Pediatrics, the Brazilian Society of Endocrinology and Metabolism, the European Society of Endocrinology, the European Society for Paediatric Endocrinology, the Latin American Society for Pediatric Endocrinology, the Pediatric Endocrine Society, and the Pediatric Pharmacy Association.¹