Investigators in France reported on 9 children aged from 10 to 45 months with hand, foot, and mouth disease (HFMD) who developed Kingella kingae osteoarticular infections.
Investigators in France reported on 9 children aged from 10 to 45 months with hand, foot, and mouth disease (HFMD) who developed Kingella kingae osteoarticular infections-K kingae being the primary cause of such infections in young children. Analysis of joint aspirations in these children also showed the presence of coxsackievirus-A6, a predominant causative agent of HFMD. Investigators noted that because HFMD virus initially replicates in the oropharynx, oropharyngeal interplays at mucosal surfaces between some HFMD virus, K kingae strains, and host cells might promote invasive infections (El Houmami NE, et al. Pediatr Inf Dis J. 2015;34:547-548).
Ms Freedman is a freelance medical editor and writer in New Jersey. She has nothing to disclose in regard to affiliations with or financial interests in any organizations that may have an interest in any part of this article.