Study does not find autism link in MMR vaccine

September 5, 2008

Strong evidence against the association of autism with the measles, mumps, and rubella (MMR) vaccine has been presented in the September 4 PLoS ONE, reported study researchers.

Strong evidence against the association of autism with the measles, mumps, and rubella (MMR) vaccine has been presented in the September 4 PLoS ONE, reported study researchers.

The case-control study consisted of an age-matched group of 25 US children with autism and gastrointestinal (GI) disturbances and 13 children with GI disturbances alone (controls). Subject were evaluated for the presence of measles virus (MV). The researchers found no differences between case and control groups in the presence of MV RNA in the ileum and the cecum. In addition, GI symptom and autism onset were unrelated to MMR timing, and 88% of autism spectrum disorder cases had behavioral regression.

The researchers concluded that autism with GI disturbances is associated with elevated rates of regression in language or other skills and may represent an endophenotype distinct from other autism spectrum disorders.