Regino P. Gonzalez-Peralta, MD

Experts in pediatric hepatology share advice for the optimal management of Alagille syndrome.

Drs Ryan T. Fischer and Regino Gonzalez-Peralta provide insight on educating patients and their caregivers on emerging treatment options for Alagille syndrome and the potential impact of evolving therapies on the progression of liver disease.

Jennifer M. Vittorio, MD, and Philip Rosenthal, MD, comment on remaining challenges for the management of patients with Alagille syndrome and discuss novel therapeutic agents under investigation for disease management.

Regino Gonzalez-Peralta, MD, reviews clinical implications from the phase 2 ICONIC trial evaluating the use of maralixibat for the management of Alagille syndrome in pediatric patients.

Jennifer M. Vittorio, MD, leads a discussion on initial treatment approaches and new drugs on the horizon for the management of persistent pruritus in patients with Alagille syndrome.

Drs Ryan T. Fischer and Regino Gonzalez-Peralta highlight the importance of tailoring treatment to a patient’s symptoms and define treatment success for Alagille syndrome.

Jennifer M. Vittorio, MD, reviews goals of therapy from early disease through progression of Alagille syndrome.

Philip Rosenthal, MD, examines monitoring requirements and follow-ups for patients with Alagille syndrome.

Regino Gonzalez-Peralta, MD, explores the role of a multidisciplinary approach to the diagnosis and management of patients with Alagille syndrome.

Experts in pediatric hepatology review health complications associated with ALGS and the importance of early diagnosis to manage the disease.

Philip Rosenthal, MD, discusses his approach to the diagnostic workup for Alagille syndrome.

Regino Gonzalez-Peralta, MD, provides insight on quality-of-life issues for patients and caregivers with Alagille syndrome.

Drs Ryan T. Fischer, William Balistreri, and Regino Gonzalez-Peralta comment on the clinical variability in the presentation of Alagille syndrome in patients.

Philip Rosenthal, MD, leads an overview of Alagille syndrome and discusses the role of genetic testing in the screening and diagnosis of disease.