News

The long latency period between exposure to an environmental trigger and cancer has already been recognized, but the same phenomenon may apply to chronic diseases such as metabolic disease and osteoporosis, with exposure to triggers in utero and early life causing disease in adulthood, according to a report published in the July 3 issue of the New England Journal of Medicine.

Survivors of the Fontan procedure, performed to correct anomalies in a functional single ventricle, still have deficits in exercise capacity but generally are doing well, according to three studies published in the July 8 issue of the Journal of the American College of Cardiology.

A vapocoolant spray provides quick pain relief for children undergoing intravenous cannulation with a higher cannulation success rate than a placebo, according to research published in the July 1 issue of CMAJ, the journal of the Canadian Medical Association.

Adolescents not only present the pediatric community with unique health problems, but are part of an often ignored age group, according to the Society of Adolescent Medicine.

A comatose teenager and a differential diagnosis of hyperammonemia eventually points to a genetic origin for the condition.

With any outdoor physical activity comes the risk of injury. This article provides an overview of running injuries specific to the pediatric population, such as strains and fractures, as well as prevention methods.

Many painful and stressful procedures are performed in neonatal intensive care units in Paris, France, and most of them are not accompanied by analgesia, researchers report in the July 2 issue of the Journal of the American Medical Association.

Population-based initiatives aimed at preventing excess weight gain complement clinical preventive strategies and treatment for obese people, according to an article published online June 30 in Circulation: Journal of the American Heart Association.

Overweight children with non-alcoholic fatty liver disease (NAFLD) are more likely to have metabolic syndrome and cardiovascular risk factors than overweight children without NAFLD, according to research published online June 30 in Circulation: Journal of the American Heart Association.

Babies who weigh more than 10 pounds at birth are twice as likely to develop rheumatoid arthritis as adults compared to babies with an average birthweight, reported researchers in the Annals of the Rheumatic Diseases.

The enterocele was partially resected in an attempt to maximize bowel length, but the intestinal tracts could not be completely separated. Postoperatively, both infants remained hypoxemic and became increasingly septic despite antibiotic therapy and critical life support. Support was ultimately withdrawn on the 65th day of life on parental request.

Two weeks before admission, he had visited the emergency department (ED) because of the headache. Migraine was diagnosed and ibuprofen had been prescribed. The headache persisted despite NSAID therapy, and the patient returned to the ED 2 days later. At that time, he had upper respiratory tract symptoms and a temperature of 39.4C (102.9F). CT scans of the head without contrast demonstrated pansinusitis with complete opacification of the frontal sinuses and frontal soft tissue swelling. The patient was admitted and given ampicillin/sulbactam intravenously for 3 days.

Dr Crane and Mr Schoonmaker, who were at the campground, write that an inordinate amount of highway traffic resulting from a local bikers' rally prevented them from transporting the patient to a medical facility. Emergent wound closure had to be performed with available materials. After the wound was flushed, a household cyanoacrylate adhesive, Krazy Glue, was used to close the laceration. To add lateral support and to reduce the risk of wound dehiscence, Dr Crane embedded hair trimmed from the patient's scalp into a second layer of glue. To replicate wound closure tape, the hair was applied perpendicular to the laceration. Azithromycin suspension was available; 1 tsp (5 mL) was given initially followed by 2.5 mL daily for 4 days.

In pre-pubertal schoolchildren in the United Kingdom, sustained physical activity above the government-recommended intensity of three metabolic equivalents of thermogenesis for 60 minutes per day is associated with improved metabolic health without affecting body mass index. But fewer than half of boys and only one in eight girls meet this guideline, according to the results of a study published online June 30 in the Archives of Disease in Childhood.