A 16-month-old with recurrent otitis media developed a spreading unilateral rash on her hip and thigh during antibiotic treatment. PCR testing confirmed herpes zoster, an uncommon diagnosis in young, vaccinated children.
News|Articles|December 26, 2025
Top 5 dermatology Puzzler case studies of 2025
Author(s)Joshua Fitch, Senior Editor
Fact checked by: Contemporary Pediatrics Staff, Justin Mancini
Join us for a recap of some of our top dermatology Puzzler cases from 2025.
Advertisement
Advertisement
Welcome to another edition of Countdown to 2026, and thank you for visiting and following Contemporary Pediatrics throughout 2025. In this edition, we present our top dermatology case studies published this year.
Related to this article
Can you guess the diagnosis?
Real-world claims show dupilumab was tied to a 33%-52% lower risk of atopic march progression vs systemic corticosteroids in children with AD.
Once-daily roflumilast cream 0.05% was well tolerated in infants 3 to <24 months with AD, with 34.4% reaching vIGA-AD success at week 4.
Oral icotrokinra kept PASI 90 rates at ≥72% and IGA 0/1 at ≥70% from week 64 to 112 in ICONIC-LEAD, with no new safety signals.
At AAP 2026, Peter Lio, MD, discussed distinguishing allergic and inflammatory skin conditions and when pediatricians should seek specialty care.
Oral icotrokinra sustained scalp, genital, and hand/foot psoriasis clearance through week 112 in ICONIC-TOTAL, with no new safety signals.
Upadacitinib showed continued facial and body repigmentation in NSV through week 76, with numerically higher responses when combined with NB-UVB.
Advertisement
Advertisement