AAP updates guidance on therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy

The American Academy of Pediatrics (AAP) has released an updated clinical report providing revised guidance on the use of therapeutic hypothermia for newborns with neonatal hypoxic-ischemic encephalopathy (HIE). The report, Therapeutic Hypothermia for Neonatal Hypoxic-Ischemic Encephalopathy, was published in the February 2026 issue of Pediatrics and updates an AAP policy statement first issued in 2014.^1,2