Secondary Syphilis in a 20-Year-Old Woman

Article

A young woman complained of multiple nonpruritic lesions on her forearms and hands; the lesions had appeared suddenly, 2 weeks earlier. More details here...


Photo courtesy of Jonathan S. Crane, DO,
Mary Lou Courreg, MD, and David Ohashi, MD


A young woman complained of multiple nonpruritic lesions on her forearms and hands; the lesions had appeared suddenly, 2 weeks earlier. Examination revealed these erythematous annular macules and papules. A biopsy specimen showed scattered plasma cells, hyperkeratosis, parakeratosis, and aggregates of mononuclear cells in the papillary dermis.

What diagnosis do these findings favor?

Please leave your comments and click here for the case discussion.

Newsletter

Access practical, evidence-based guidance to support better care for our youngest patients. Join our email list for the latest clinical updates.

Recent Videos
Contemporary Pediatrics: RX Review: Updates and Unmet Need in RSV thumbnail
Contemporary Pediatrics: RX Review: Updates and Unmet Need in RSV thumbnail
Contemporary Pediatrics: RX Review: Updates and Unmet Need in RSV thumbnail
Staphylococcus aureus risk in infants and neonatologist considerations with Aaron Milstone, MD
How fragrance plays a role in atopic dermatitis treatments, with John Browning, MD
Octavio Ramilo, MD, reacts to the FDA approval of clesrovimab for RSV prevention | Image Credit: St. Jude Children's Research Hospital
© 2025 MJH Life Sciences

All rights reserved.