Pediatric drug development has made exceptional strides in the last 10 years. The outlook going forward is remarkably positive, but new pressures to expedite the process are emerging.
Proton pump inhibitors often are prescribed to treat infants with symptoms suspected as gastroesophageal reflux disease, but these acid-suppressing drugs are not safe for infants younger than 12 months.
Social phobia is not just an extreme form of shyness in most teenagers, and it often requires referral and/or intervention from a pediatrician, according to recent research. In a recent study, 12% of teens who identified themselves as shy met the criteria for social phobia, and another 5% of those who did not consider themselves shy also met the diagnostic criteria. You may be surprised to discover how rare it is for adolescents with social phobia, even those with significant impairment, to receive treatment.
With influenza being one of the most common reasons for hospitalization of children, finding the most effective vaccination combination is increasingly important. That?s what researchers recently set out to do, finding that although the live attenuated influenza vaccine nasal spray and trivalent inactivated influenza vaccine shots are effective, only the nasal spray may confer additional immunity. Could a change in guidelines be on the horizon?
For many pediatricians, trimethoprim-sulfamethoxazole (TMP-SMX) may be the oral antibiotic of choice when a patient presents with a community-associated methicillin-resistant Staphylococcus aureus skin infection, but another drug?clindamycin?may actually work better, according to a new study. Find out why the experts recommend clindamycin, even though there seemed to be good reasons to prescribe TMP-SMX.
Although drug regimens such as the protease inhibitor lopinavir-ritonavir may have lowered the HIV transmission rates in newborns to less than 1%, a study finds that postnatal treatment with the combination was more likely to cause adrenal dysfunction in newborns when compared with a zidovudine-based treatment. Read about the nuances of the study and the researchers? recommendations.
FDA has received reports of hepatosplenic T-cell lymphoma in adolescents and young adults with Crohn's disease and ulcerative colitis being treated with tumor necrosis factor blockers, azathioprine, and mercaptopurine.
The Food and Drug Administration has approved use of the drug Protopam (pralidoxime) as an antidote to pesticide poisoning in pediatric patients.
Parents' attitudes toward postop pain management in their children reflected in underuse of analgesics
Parents' misperception of analgesics leads to the undertreatment of postoperative pain in their children, even though the parents are aware of their children's pain, according to a new study.
The Food and Drug Administration has approved the human growth hormone Omnitrope (somatropin - rDNA origin) for the treatment of idiopathic short stature.