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pJIA can lead to an increased risk of permanent joint damage as well as delayed growth and development.

Overall, the findings of the study support the clinical utility of combining trio-WES sequencing with CNV-seq in the etiologic diagnosis and management of early-childhood GDD.

Once-daily, steroid-free, topical roflumilast cream 0.15% has a PDUFA date of July 7, 2024.

The authors indicate that delays in diagnosis of endometriosis can lead to disease progression and an impact on fertility, whereas early diagnosis and appropriate management may result in less major surgery in adulthood.

Get caught up with our journal! Review some of the top stories from the Contemporary Pediatrics website over the last week, and catch up on anything you may have missed.

The 2-drug, fixed-dose combination tablet contains darunavir, an HIV-1 protease inhibitor, and cobicistat, a CYP3A inhibitor that serves as a PK enhancer or “booster.”

Investigators developed an algorithm indicating that only 7.7% of patients with BHS require an ECG at BHS diagnosis, a much lower proportion than the 45.1% of those who had undergone the test in the study sample.

Over the winter, the omicron JN.1 lineages overtook XBB strains as dominant.

Though some drowning prevention strategies seem common or routine, data demonstrate drowning deaths among children have risen in recent years, which should prompt conversations with families on refreshers and new prevention initiatives.

The 2 groups did not differ in how likely they were to fill at least 1 prescription of any antibiotic while enrolled in kindergarten.

Pediatricians may eventually realize a significant increase in income by attaching the G2211 code to acute and chronic care visits.

As safe and effective gene-editing and gene-replacement therapies become more attainable, developing the delivery systems that ensure these treatments are equitably available will be equally essential.

Following evidence from recent studies, the CDC has recommended the use of doxycycline postexposure prophylaxis in sexual health among certain populations.

Additionally, a new weight-based oral solution, RINVOQ LQ, is now available as an option for the pediatric populations.

Management of ICEP with monoclonal antibodies against IL-5 and IgE (omalizumab) could be promising according to study authors, though extent of evidence is lacking.

Mesoblast Limited's chief executive announced a BLA resubmission for remestemcel-L is expected to be filed with the FDA this quarter.

The maximum daily dose has increased from 80 mg to 100 mg.

Editor-in-chief Tina Tan, MD, FAAP, FIDSA, FPIDS, highlights the June 2024 issue of Contemporary Pediatrics.

Get caught up with our journal! Review some of the top stories from the Contemporary Pediatrics website over the last week, and catch up on anything you may have missed.

The disorders can impact the academic and social functioning of college students and have been associated with long-term health issues.

Prior to the federal agency's decision, children aged 5 years and older could only receive belimumab through an intravenous (IV) formulation.

The therapy was previously granted accelerated approval for the thyroid cancer indications in adults and pediatric patients aged 12 years and older.

Analysis demonstrated a significant correlation between elevated levels of serum circulating magnesium and serum vitamin D with increased risk of childhood asthma. 

The once daily extended-release oral suspension with nighttime dosing is approved to treat ADHD as a monotherapy or as an adjunctive therapy to approved CNS stimulant medications.

Peanut consumption starting in infancy resulted in lasting tolerance into adolescence.

Findings indicate that chronically high stress markers could have a role in the development of EF impairments in early adolescents with cCHD.

A recent study suggests that high ultraprocessed food consumption in preschool children is linked to increased cardiometabolic risk factors.

New international findings show BPD diagnosis in teenaged years may be a critical indicator of subsequent mental disorder into young adulthood.