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Results from a pivotal phase 2 clinical trial revealed axatilimab met the primary outcome in all cohorts for graft versus host disease (GVHD) in pediatric and adult patients. Based on its safety and efficacy profile demonstrated in clinical trials, Syndax and Incyte intend to file a biologics license application (BLA) for axatilimab with the FDA by the end of 2023.

Researchers analyze ChatGPT for summarizing medical records.

The fully online training program, the MOPD Foundations of Pediatric Dermatology Certificate Course, was created by the founders of the Masters of Pediatric Dermatology (MOPD) Symposium and includes lectures, presentations, and downloadable resources for clinicians.

Results from this active, facility-based surveillance study revealed hospitalization rates for children younger than 5 years were 1.7 to 7.1 times higher among American Indian and Alaska Native children compared to estimates from the methodologically similar US New Vaccine Surveillance Network (NVSN).

Donna Hallas, PhD, PPCNP-BC, CPNP, PMHS, FAANP, FAAN, recaps her thoughts on the latest issue of Contemporary Pediatrics.

In this study, investigators focused on children with Fetal Alcohol Spectrum Disorder (FASD), who are known to experience significant sleep disturbances.

Following the resubmission of a new drug application, the FDA has approved VP-102 to treat molluscum contagiosum, a contagious skin disease transmitted through direct skin-to-skin contact that primarily affects children.

Data corresponding with DSM-IV symptoms were gathered around ages 18, 21, and 23 years and the primary outcome was depression at age 24.

In a recent study, higher immunoglobulin G titers were seen in infants of mothers who received messenger RNA COVID-19 vaccination during pregnancy.

According to Pfizer, the investigational vaccine to protect against Group B Streptococcus (GBS) generated maternal antibody responses against 6 capsular polysaccharide serotypes and efficiently transferred antibodies to the infants. The announcement of this phase 2 data comes in July, which is International Group B Streptococcus Month.

Lorazepam, diazepam, midazolam, fentanyl, hydromorphone, morphine, ketorolac, epinephrine, diphenhydramine, and methylprednisolone were investigated in the study. Overall, the most common type of deviation was an underdose.

A follow-up to an earlier study, the latest research leveraged EHR data from medical centers in North Carolina and concluded incident cases of type 1 diabetes increased nearly 50% and incident cases of type 2 diabetes more than doubled in 2021-2022 relative to prepandemic years.

Overall, results from the report demonstrated that cannabis-involved emergency department (ED) visits for individuals under 25 years increased during the pandemic. For those aged 10 years or younger, the weekly number of cannabis-involved ED visits during the pandemic far exceeded the number of visits observed prepandemic.

Using 3 complementary statistical approaches of linear modeling, Bayesian, and multigroup factor analysis, investigators determined IQ scores are not negatively impacted by pediatric concussion up to 3 months postinjury.

More symptoms, older age, and longer hospitalization time increased the risk of post-COVID-19 conditions (long COVID) in children.

Health care continues to be a top target for hackers.

John Bradley, MD, medical director, infectious disease, Rady Children's Hospital, San Diego, California; professor of pediatrics, UC San Diego School of Medicine, explains how recently FDA-approved nirsevimab-alip will impact the newborn and infant RSV patient population.

Researchers hope a new study will alleviate patients and clinicians fear of prescribing stimulants for children with ADHD.

According to the report, 34% of parents are using patient portals for advice regarding their child’s illness.

The approval follows a unanimous vote of support from the FDA Antimicrobial Drugs Advisory Committee of nirsevimab-alip’s favorable benefit-risk profile for the prevention of Respiratory Syncytial Virus (RSV) lower respiratory tract disease (LRTD) in newborns and infants amid their first RSV season.

The study revealed several concerning trends in the utilization of acute mental health care among youth during the second year of the COVID-19 pandemic.

Mike Hennessy JR, President and CEO, MJH Life Sciences, gives readers a company-wide update regarding a 2023 company acquisition and Strategic Alliance Partnerships.

The FDA has identified NOxBOX Ltd’s recall of NOxBOXi Nitric Oxide Delivery System as a Class I recall. Affected devices to the newborn and neonate patient populations can cause nitric oxide therapy interruptions because of a check valve misalignment. As of July 13, 2023, no injuries or deaths have been reported according to the federal agency.

GLP-1 receptor agonists, used to treat diabetes, are now also being used for obesity in children and adolescents.

You are called to the hospital nursery to evaluate a healthy full-term newborn boy who developed painful flaccid blisters and erosions on the tops of his feet and ankles shortly after birth. His mother had a history of similar recurrent skin lesions that healed with scarring. She also had oral and gastrointestinal tract involvement. What's the diagnosis?

To better protect children from its several negative effects, the Environmental Protection Agency (EPA) has proposed stricter requirements for lead-based paints in pre-1978 buildings and childcare facilities.

A 5-week-old female infant born at 38 weeks presents to her pediatrician with abnormal eye movements. What’s the diagnosis?

Norgestrel (Opill; HRA Pharma) is the first nonprescription oral contraceptive approved for use in the United States.

Despite several health and nutrition claims on breast milk substitutes and infant formula products, little to no evidence supported these claims in a multicountry study published in BMJ.

A resurgence of this infection, particularly in the pediatric population, has health care providers on alert.