Deepak M. Kamat, MD, PhD

A 14-year-old girl with systemic lupus erythematosus (SLE) was evaluated for worsening left leg pain of 1 week’s duration. A month earlier, she had presented with left knee arthritis and a vasculitic rash; the antinuclear antibody titer was positive. In addition, she had leukopenia, myositis, hypocomplementemia, and mild proteinuria.

A 13-year-old boy was brought to the emergency department (ED) with a generalized itchy rash of 2 days' duration. For the past 3 days, he had dry, itchy eyes with a purulent discharge (Figure 1) and nonbilious emesis 2 or 3 times per day, with some blood streaks in the vomitus on the third day of illness.

A 4-year-old girl was brought to the emergency department after she sustained an injury to her jaw in a car accident. She had been restrained in the rear passenger seat with a seat belt. She had not lost consciousness and was not ejected from the vehicle.

A previously healthy 16-month-old boy was hospitalized because of vomiting of 10 days' duration, fever of 4 days' duration (temperature up to 38.6°C [101.4°F]), and watery diarrhea. He also had had a maculopapular rash, which resolved the day before presentation. Family history was unremarkable.

In addition to syringohydromelia and meningocele, the MRI of the spine showed a fluid-filled mllerian duct remnant that extended from the base of the bladder to the posterior superior aspect of the prostate gland. The margins of the fluid collection in the remnant are smoothly bound by a hypointense structure that represents a discrete tissue wall. A mllerian duct remnant can be confused with free fluid in the cul-de-sac posterior to the bladder.

This fairly common phenomenon, also known as Mongolian spots, affects more than 90% of African Americans, 80% of Asians, 46% of Hispanics, and fewer than 10% of Caucasians.1 The bluish gray or slate-colored areas occur most frequently on the lower back and buttocks and less frequently on the posterior thighs, legs, back, and shoulders. The face is rarely affected. The skin coloration is believed to be caused by melanocyte migration arrest from the neural crest to the epidermis.

The enterocele was partially resected in an attempt to maximize bowel length, but the intestinal tracts could not be completely separated. Postoperatively, both infants remained hypoxemic and became increasingly septic despite antibiotic therapy and critical life support. Support was ultimately withdrawn on the 65th day of life on parental request.

The infant's father and sister had similar toe deformities. Radiographs of the feet revealed no bone abnormalities. The patient was referred to a pediatric orthopedist to reassure the mother.

A 14-year-old white girl whose menstrual periods have not begun presents with concerns that many of her peers are already menstruating.

Results of a complete blood cell count (CBC), measurements of electrolyte concentrations, and urinalysis were normal. A rapid streptococcal test result was negative. The C-reactive protein level was elevated at 3.3 mg/L (normal, less than 1 mg/L); the erythrocyte sedimentation rate was 58 mm/h (normal, 4 to 20 mm/h).

Vital signs were normal. Soft tissue swelling of the left foot and ankle was nonsignificant; there was no obvious deformity. Point tenderness was marked over the medial malleolus and over the shaft of the fifth metatarsal distally. The remaining physical findings were normal.

Alignment. Accommodative esotropia is treated initially with glasses. The glasses may not improve visual acuity. They are used so the child does not have to make the accommodative effort; the eyes may not "turn in" and the child can use the eyes together, binocularly. If the eyes are aligned with spectacle correction, surgery may never be required. However, if the eyes are not aligned with glasses and/or bifocals, or if the child cannot be weaned from bifocals as he or she grows, then surgery may be indicated. We all lose our ability to accommodate for near tasks as time goes by-the loss of accommodative effort over time is of benefit to children with accommodative esotropia, because they may outgrow the need for glasses and avoid muscle surgery.

Ultrasonography showed a large multiseptated cystic mass in the posterior part of the left side of the neck. No obvious vascular flow evident within the mass (Figures 3 and 4).

The 2-year-old boy shown here had been bitten on the left cheek by a medium-sized dog while at the home of his day-care provider. Immediately after the incident, the child was examined by his pediatrician and given a presciption for amoxicillin clavulanate. The next day, he presented to the emergency department with worsening cellulitis of the left cheek.

The "Baghdad boil," as it is known in Iraq, usually begins as a papule at the site of a sandfly bite. This progresses to a nodule and then an ulcer, which eventually crusts over. The ulcer is typically painless, unless infected. The female sandfly is a common vector of transmission of cutaneous leishmaniasis. Most cases are caused by Leishmania major in dry desert areas and Leishmania tropica in urban areas. Tissue biopsy remains the gold standard diagnostic test for the disease.2,4,5

This skin abnormality is cutis marmorata-a physiological dilatation of capillaries and venules of the trunk and extremities in infants and young children caused by exposure to cold. The discoloration fades with warming, as was the case with this baby. The condition is seen especially when subcutaneous fat is decreased.

Numerous scattered, mildly erythematous, brownish papules were scattered over the trunk, upper extremities, buttocks, and upper thighs. Many were slightly scaly and several had developed an eschar. The patient also had multiple areas of postinflammatory hyperpigmentation and a few varioliform scars. Other examination findings were normal.

Routine screening for eye disease at all well-child visits should begin in the newborn period. Prompt ophthalmological referral of patients with strabismus or any suspected eye disease is essential to determine the underlying cause, optimize treatment, and preserve binocular vision

ABSTRACT: Routine screening for eye disease at all well-child visits should begin in the newborn period. Prompt ophthalmological referral of patients with strabismus or any suspected eye disease is essential to determine the underlying cause, optimize treatment, and preserve binocular vision.

As a clinical immunologist with a special interest in vaccines, it is a pleasure to present this special issue of Consultant For Pediatricians. Vaccines are among the major achievements of modern medicine. Once common serious childhood illnesses, including tetanus, diphtheria, polio, mumps, and measles, are now rarely seen in this country. It is ironic, therefore, that with the precipitous decline in the incidence of many infectious diseases brought about by widespread vaccination--and the very recent availability of several new vaccines--many parents have been lulled into a false sense of security about the risk posed by the diseases these vaccines have been designed to prevent.

ABSTRACT: Because almost one tenth of American children aged 2 to 11 years have untreated tooth decay, a physical examination that includes inspection of the mouth is crucial. Look for cavitated or noncavitated lesions, dental fillings, and missing teeth; gingivitis and/or plaque, chalky white spots, or deep fissures on the teeth suggest dental decay. Dental care strategies that can be discussed at well-child visits include the benefits of daily flossing and brushing with fluoridated toothpaste, limited intake of dietary sugar, the establishment of a dental home, and use of protective mouthguards and face protectors during sport activities. Fluoride supplementation can be prescribed for children exposed to inadequate amounts in the water supply. The Caries-Risk Assessment Tool can help identify children at high risk for tooth decay. The pediatrician can have a great impact on ensuring that children obtain necessary dental care; a literature review found that children referred to a dentist by a primary care provider were more likely to visit a dentist than those not referred.

A 4-year-old girl was brought to a local emergency department (ED) after an episode of dizziness, vomiting, and horizontal nystagmus.

A 6-month-old white girl presented with a 2-day history of fever and respiratory symptoms. Initially, she was admitted with a diagnosis of respiratory syncytial virus bronchiolitis. In addition to her respiratory findings, widespread signs of rickets were found--ie, frontal bossing, rachitic rosary, widening of the wrists, and double maleoli.

Consultations & Comments: "Focus on Vaccines" Correction: MMR Never Contained Thimerosal

ABSTRACT: Because foreign-body aspiration can cause symptoms that mimic those of other respiratory conditions, a high index of suspicion is crucial in all children who have pneumonia, atelectasis, or wheezing with an atypical course--especially when these conditions are unresponsive to usual medical therapy. A history of choking can usually be elicited in a patient who has aspirated a foreign body: such a history should be sought when respiratory symptoms develop suddenly. However, the absence of a choking history does not rule out foreign-body aspiration. Moreover, patients may be asymptomatic initially. Normal radiographic findings do not exclude an aspirated foreign body. Bronchoscopy should be strongly considered when an aspirated foreign body is suspected, even if radiographic images show normal findings. Rigid bronchoscopy is the procedure of choice for removing aspirated foreign bodies in children. Prevention of foreign-body aspiration can be enhanced through anticipatory guidance of parents/caregivers and through continued product safety efforts.

This 6-month-old boy was born with a pigmented hairy nevus that covered about 80% of his body surface. Multiple pigmented satellite lesions were also present.

Foreign-body aspiration is a relatively common occurrence in children. It may present as a life-threatening event that necessitates prompt removal of the aspirated material. However, the diagnosis may be delayed when the history is atypical, when parents fail to appreciate the significance of symptoms, or when clinical and radiologic findings are misleading or overlooked by the physician.

Head shape abnormalities in infants may be the result of pressure on the malleable bones in the newborn skull during a vaginal delivery (molding), of constant gravitational forces on the occiput when an infant is kept in the same supine position for prolonged periods (positional deformational plagiocephaly), or of premature fusing of one or more of the cranial sutures (craniosynostosis).

A 45-day-old boy was referred for evaluation of persistent hyponatremia and hyperkalemia. On the 9th day of the boy's life, his serum potassium level was elevated (8 mEq/L) and on the 12th day, his serum sodium level was low (131 mEq/L). Supplementation with sodium chloride was initiated.

Chest pain in children evokes anxiety in patients and their parents--and prompts frequent visits to the pediatrician's office, urgent care facility, or emergency department (ED). In a prospective study, Selbst and colleagues reported that chest pain accounted for 6 in 1000 visits to an urban pediatric ED.