October 29th 2025
A pair of phase 3 trials showed that AbbVie's daily upadacitinib 15 mg led to a 50% reduction in T-VASI 50 and a 75% reduction in F-VASI 75 at 48 weeks among adolescents 12 years and older.
Eucrisa approved for AD use in infants aged 3 months and older
April 1st 2020The US Food and Drug Administration has given approval for a supplemental new drug application for Eucrisa (crisaborole) that allows the nonsteroidal topical ointment to be used for treating mild-to-moderate atopic dermatitis (AD) in children aged as young as 3 months.
Boy’s chronic lesions change with the seasons
November 8th 2019A healthy 10-year-old male presents for evaluation with a 3-year history of an asymptomatic and progressive, mildly pruritic rash over his head and trunk. The first lesion appeared on his back 3 years ago, and numerous other lesions developed insidiously afterward. The patient’s father states that the lesions fade during the winter and become more prominent during the summer. Failed treatment included hydrocortisone. What's the diagnosis?
Erythematous plaque on an infant’s cheek
October 10th 2019A healthy, afebrile, 12-month-old girl presents for evaluation with an asymptomatic nodule on her left cheek that has been present for 3 weeks. She was initially seen by her pediatrician, diagnosed with cellulitis, and prescribed an oral antibiotic, which was not administered by her parents.
How treating food allergies and AD has changed
September 27th 2019Food allergies are a hot topic on the playground, at schools, and in pediatric offices. Parents of children with eczema or atopic dermatitis (AD) often have a lot of questions regarding the connection between eczema, exposure to common food allergens, and the development of or exacerbation of AD. There are many of the complex questions that clinicians must answer when evaluating pediatric patients with AD.
Sunscreen ingredients are absorbed systemically
August 6th 2019Applying sunscreen as often as manufacturers recommend results in plasma concentrations of sunscreen’s 4 active ingredients that exceed the threshold for safety concerns established by the US Food and Drug Administration (FDA), according to a recent study.
Fuzzy brown spots on a healthy 3-year-old
June 19th 2019A healthy 3-year-old girl presents for evaluation of light brown spots on her trunk and extremities that have appeared over the last 2 years. The spots are not symptomatic but the girl’s parents are worried that she could have neurofibromatosis.
Painful, tense acral bullae in a 12-year-old girl
March 1st 2019A healthy 12-year-old girl presents to the clinic with 2 days of low-grade fever and enlarging, painful, tense bullae on both hands. She had recently been diagnosed with streptococcal pharyngitis and was being treated with oral cefixime.
Reticulated rash on boy’s lower extremities
February 1st 2019A healthy 11-year-old boy is brought to the office for evaluation of asymptomatic reticulated rash that started on his ankles 3 weeks ago and since has spread to his shins and the tops of both feet. He is on no medications and has had no history of trauma or recent illness. What's the diagnosis?
Streaky pigmentation suggests larger issues
January 1st 2019The parents of a 2-month-old boy return to the office for a well-child visit. The infant has a history of hypotonia and poor head control but is growing normally. His parents noted streaky patterns of hypopigmentation over his trunk and extremities shortly after birth and felt they were likely just “birthmarks.”
Persistent pruritic rash in an 8-year-old boy
November 1st 2018An 8-year-old boy is brought to the office for evaluation of a persistent itchy rash on his extremities, trunk, and face. Although the rash has been present for longer than 3 months, individual skin lesions change from hour to hour and occasionally the rash clears completely only to recur several hours later. He is otherwise healthy with no known allergies, changes in diet, medication use, or recent illness.