June 16th 2025
The approval for ustekinumab-stba now offers all dosage forms to the reference product, ustekinumab, and is indicated for patients aged 6 to 17 years.
A Tethered Approach to Type 2 Diabetes Care – Connecting Insulin Regimens with Digital Technology
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Surv.AI Says™: What Clinicians and Patients Are Saying About Glucose Management in the Technology Age
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Addressing Healthcare Inequities: Tailoring Cancer Screening Plans to Address Inequities in Care
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Cases and Conversations™: Applying Best Practices to Prevent Shingles in Your Practice
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Case In Point: Infantile Hypertrophic Pyloric Stenosis
A 7-week-old white boy presented to the emergency department (ED) with vomiting and weight loss. His parents brought him to the ED 3 weeks earlier after he had vomited for several days. Possible milk protein allergy was diagnosed at that visit, and a change from cow milk formula to an elemental formula was recommended. Vomiting subsequently increased in frequency. Nonbilious but forceful vomiting occurred with each feeding. The patient lost nearly 2 lb during the 3 weeks that followed the first ED visit.
Psoriasis in an 11-Month-Old Infant
February 1st 2006An otherwise healthy 11-month-old infant hadhad an intermittent, nonpruritic rash for mostof his life. The lesions recurred mainly onthe extremities and trunk without a particulartrigger. Applications of 1% hydrocortisonecream were only partially beneficial. The joints and nailswere not affected. The patient’s maternal grandfather hadsevere psoriasis.
WHAT'S YOUR DIAGNOSIS? Six-month-old girl with dysmorphic appearance referred for genetic evaluation
February 1st 2006Six-month-old girl with dysmorphic appearance referred for genetic evaluation. Child is a product of a fraternal twin pregnancy; born at 41 weeks gestational age. Mother, age 32, received no prenatal care. Paternal age, 41 years.
Surprise revelation: Dermatologist's novel head lice treatment is an OTC skin wash
January 13th 2006After an unsuccessful attempt to persuade pharmaceutical companies to fund further research on a head lice treatment he says he discovered and developed, dermatologist Dale Pearlman, MD, has revealed that the treatment is actually a brand-name over-the-counter skin cleanser.
Photoclinic: Keloid at the Site of a Chickenpox Lesion
January 1st 2006An 18-year-old girl presented with an asymptomatic nodule on the posterior aspect of the right upper arm. The lesion had developed a month after an episode of chickenpox at 11 years of age and had slowly enlarged. The lesion was 7 mm in diameter; it was firm, rubbery, reddish brown, and nontender.
Photoclinic: MRSA Skin Abscess and Osteomyelitis
January 1st 2006This lesion on the chest of a 6-week-old infant had developed over 2 days (A). It began as a small mass just below the right nipple. Initially, there was no tenderness or erythema; within 2 days, the lesion had begun to drain green-yellow and then white purulent exudate.
Genetic Disorders: Toddler With Skeletal, Ocular, and Cardiac Anomalies
January 1st 2006A 15-month-old girl presents for evaluation of macrocephaly and unusual facial features. Her prenatal and natal history are unremarkable. The child is now developing normally after mild gross motor delays during the first 6 months of life. Mild scoliosis was noted on a babygram taken at 8 months during an evaluation for possible nonaccidental trauma.
A 9-Year-Old Girl With Eruptions and Malaise
January 1st 2006A 9-year-old girl presented with these lesions on her face and extremities. The lesions, which had developed within the past 24 hours, were warm to the touch and only mildly pruritic. The child feels unwell with nonspecific complaints of malaise and lack of energy. Before this eruption, she had been healthy and had not been taking any medications.
A hairy predicament: "Why is my toddler going bald?"
December 1st 2005The mother of a 3-year-old boy has brought him to the clinic for you to evaluate thinning of his scalp hair over the past month. She reports that the hair loss is occurring "all over" his scalp and that she has not noticed him scratching his scalp or pulling his hair. He was hospitalized four months ago for a rotavirus infection.
What’s Wrong With This Picture? Child With Fever and Persistent Cough
December 1st 2005A2¹⁄₂-year-old child is hospitalized with a 1-monthhistory of worsening persistent cough. She was initiallytreated with a 5-day course of oral amoxicillin, andher symptoms abated somewhat. However, for the pastweek, she has experienced high fever (temperatures upto 38.3°C [101°F]) and chills associated with right-sidedpleuritic chest pain.
Just plain bad news confirmed: The childhood melanoma rate is rising
November 4th 2005The rate of melanoma among children and young adults rose dramatically between 1973 and 2001, according to a study in a recent issue of the Journal of Clinical Oncology. "Between the years 1973 and 2001, the incidence of pediatric melanoma increased 2.9% per year and 46% per year of age," says John Strouse, MD, a pediatric oncologist and instructor in pediatrics at the Johns Hopkins University and author of the article.
Allergic conditions exact a heavy toll, says specialist
October 11th 2005Allergic diseases are the sixth leading cause of chronic disease in the United States and cost the health-care system more than $18 billion a year. But despite the seriousness suggested by these numbers, many people don't understand how deflating allergies can be to quality of life for patients and families, according to Mark Boguniewicz, MD, professor at Denver's National Jewish Medical and Research Center.
Cold Injuries: A Guide to Preventing--and Treating--Hypothermia and Frostbite
October 1st 2005ABSTRACT: Hypothermia is not limited to the northern states: people also die of hypothermia in other areas with milder climates. Infants, young adolescent boys, and inadequately dressed teens who abuse alcohol or illicit drugs are at highest risk for death secondary to hypothermia. The mildly hypothermic patient may appear fatigued and display persistent shivering, ataxia, clumsiness, confusion, tachypnea, and tachycardia. The child with moderate hypothermia will not be shivering; declining mental status may cause the freezing patient to remove clothing. An irregular heartbeat is likely at this stage. Severe hypothermia is marked by apnea, stupor, and coma. In a frostbitten patient, rapid rewarming of the affected area in warm water for 15 to 30 minutes is the first step. Potent analgesia is often necessary. After thawing, the frostbitten part is kept dry, warm, and loosely covered. With an adequate dose of common sense, the vast majority of deaths from cold injury can be prevented.
Case In Point: Eczema Herpeticum: An Uncommon Complication of Atopic Dermatitis
October 1st 2005A 2-year-old boy was brought for evaluation of a rash and fever of 2 days' duration. He had atopic dermatitis since 6 months of age that was partially controlled with low-potency topical corticosteroids and emollients. His father reported that recently the facial dermatitis had worsened, with increased redness, pain, and some skin breakdown. The child's medical history was otherwise unremarkable. His mother had a history of "cold sores."